Scaffolds, nanoparticles and drugs: a multifaceted approach to reduce scarring

[Truncated] Scarring represents a huge global burden with billions of dollars spent annually on the treatment of scars. In the developed world, 100 million people develop scars annually and with recent advances in care decreasing mortality, the improvement of scar outcomes and recovery of patient function has become increasingly important. Despite extensive research focused on the mechanisms responsible for scar formation, there are currently no widely accepted, clinically effective products for the treatment or prevention of scarring. There is therefore a need to develop economical, efficient and widely available therapeutic approaches to enhance would healing and ameliorate scarring.