SARS-CoV-2 Infection and Childhood Islet Autoimmunity

ENDIA Study Group; Elizabeth A. Davis; Aveni Haynes; Grant Morahan

doi:10.1001/jamapediatrics.2024.6848

SARS-CoV-2 Infection and Childhood Islet Autoimmunity

Research output: Contribution to journal › Letter › peer-review

Abstract

Increased incidence of type 1 diabetes (T1D) has been observed during the COVID-19 pandemic.1 In children who were genetically at risk, SARS-CoV-2 infection was associated with increased risk of islet autoimmunity (IA) in some longitudinal cohorts2 but not others.3 Additionally, COVID-19 may accelerate progression to clinical T1D in children with IA.4 We investigated the potential temporal association between SARS-CoV-2 infection and the development of IA in the longitudinal Australian Environmental Determinants of Islet Autoimmunity (ENDIA) study.

Original language	English
Pages (from-to)	568-570
Number of pages	3
Journal	JAMA Pediatrics
Volume	179
Issue number	5
Early online date	3 Mar 2025
DOIs	https://doi.org/10.1001/jamapediatrics.2024.6848
Publication status	Published - 5 May 2025

Funding

Funders	Funder number
NHMRC National Health and Medical Research Council	1025083, 2026105, 2021404, 2032781

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1001/jamapediatrics.2024.6848Licence: CC BY

Cite this

@article{2d05b6a57d1f4b7f9474eb649a63a302,

title = "SARS-CoV-2 Infection and Childhood Islet Autoimmunity",

abstract = "Increased incidence of type 1 diabetes (T1D) has been observed during the COVID-19 pandemic.1 In children who were genetically at risk, SARS-CoV-2 infection was associated with increased risk of islet autoimmunity (IA) in some longitudinal cohorts2 but not others.3 Additionally, COVID-19 may accelerate progression to clinical T1D in children with IA.4 We investigated the potential temporal association between SARS-CoV-2 infection and the development of IA in the longitudinal Australian Environmental Determinants of Islet Autoimmunity (ENDIA) study.",

author = "\{ENDIA Study Group\} and Walker, \{Gregory J.\} and Kylie-Ann Mallitt and Craig, \{Maria E.\} and Pat Ashwood and Barry, \{Simon C.\} and Brown, \{James D.\} and Joanna Caguicla and Davis, \{Elizabeth A.\} and Hamilton-Williams, \{Emma E.\} and Harrison, \{Leonard C.\} and Aveni Haynes and Tony Huynh and Guinevere Martin and Mcgorm, \{Kelly J.\} and Grant Morahan and Zin Naing and Helena Oakey and Penno, \{Megan A. S.\} and Andrea Sevendal and Sinnott, \{Richard O.\} and Georgia Soldatos and Thomson, \{Rebecca L.\} and Jason Tye-Din and Vuillermin, \{Peter J.\} and Ward, \{Emily J.\} and Wentworth, \{John M.\} and Colman, \{Peter G.\} and Couper, \{Jennifer J.\} and Kim, \{Ki Wook\} and Rawlinson, \{William D.\}",

year = "2025",

month = may,

day = "5",

doi = "10.1001/jamapediatrics.2024.6848",

language = "English",

volume = "179",

pages = "568--570",

journal = "JAMA Pediatrics ",

issn = "2168-6203",

publisher = "American Medical Association",

number = "5",

}

TY - JOUR

T1 - SARS-CoV-2 Infection and Childhood Islet Autoimmunity

AU - ENDIA Study Group

AU - Walker, Gregory J.

AU - Mallitt, Kylie-Ann

AU - Craig, Maria E.

AU - Ashwood, Pat

AU - Barry, Simon C.

AU - Brown, James D.

AU - Caguicla, Joanna

AU - Davis, Elizabeth A.

AU - Hamilton-Williams, Emma E.

AU - Harrison, Leonard C.

AU - Haynes, Aveni

AU - Huynh, Tony

AU - Martin, Guinevere

AU - Mcgorm, Kelly J.

AU - Morahan, Grant

AU - Naing, Zin

AU - Oakey, Helena

AU - Penno, Megan A. S.

AU - Sevendal, Andrea

AU - Sinnott, Richard O.

AU - Soldatos, Georgia

AU - Thomson, Rebecca L.

AU - Tye-Din, Jason

AU - Vuillermin, Peter J.

AU - Ward, Emily J.

AU - Wentworth, John M.

AU - Colman, Peter G.

AU - Couper, Jennifer J.

AU - Kim, Ki Wook

AU - Rawlinson, William D.

PY - 2025/5/5

Y1 - 2025/5/5

N2 - Increased incidence of type 1 diabetes (T1D) has been observed during the COVID-19 pandemic.1 In children who were genetically at risk, SARS-CoV-2 infection was associated with increased risk of islet autoimmunity (IA) in some longitudinal cohorts2 but not others.3 Additionally, COVID-19 may accelerate progression to clinical T1D in children with IA.4 We investigated the potential temporal association between SARS-CoV-2 infection and the development of IA in the longitudinal Australian Environmental Determinants of Islet Autoimmunity (ENDIA) study.

AB - Increased incidence of type 1 diabetes (T1D) has been observed during the COVID-19 pandemic.1 In children who were genetically at risk, SARS-CoV-2 infection was associated with increased risk of islet autoimmunity (IA) in some longitudinal cohorts2 but not others.3 Additionally, COVID-19 may accelerate progression to clinical T1D in children with IA.4 We investigated the potential temporal association between SARS-CoV-2 infection and the development of IA in the longitudinal Australian Environmental Determinants of Islet Autoimmunity (ENDIA) study.

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=uwapure5-25&SrcAuth=WosAPI&KeyUT=WOS:001439230300001&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.1001/jamapediatrics.2024.6848

DO - 10.1001/jamapediatrics.2024.6848

M3 - Letter

C2 - 40029632

SN - 2168-6203

VL - 179

SP - 568

EP - 570

JO - JAMA Pediatrics

JF - JAMA Pediatrics

IS - 5

ER -

SARS-CoV-2 Infection and Childhood Islet Autoimmunity

Abstract

Funding

UN SDGs

Access to Document

Other files and links

Fingerprint

Project Grants - Early Environmental Determinants of Pancreatic Islet Autoimmunity: A Pregnancy to Early Life Cohort Study in Children at Risk of Type 1 Diabetes

Cite this

SARS-CoV-2 Infection and Childhood Islet Autoimmunity

Abstract

Funding

UN SDGs

Access to Document

Other files and links

Fingerprint

Projects

Project Grants - Early Environmental Determinants of Pancreatic Islet Autoimmunity: A Pregnancy to Early Life Cohort Study in Children at Risk of Type 1 Diabetes

Cite this