Sampling disturbance is an important consideration when interpreting geotechnical parameters from laboratory data to ensure reliable and economical geotechnical designs. The study includes extensive soil experimental testing as well as physical modelling to evaluate sampling disturbance in fine-grained soils. The consequences of sampling disturbance in soft clay were illustrated in the design of an embankment and shallow foundation, using data measured on samples obtained with different sampling methods. The effects of tube penetration rates and corresponding drainage conditions in carbonate silty soils were studied using two physical model. Some recommendations were proposed to improve the sampling process in fine-grained soils.