Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis

Yongjuan Guan; G. Liang; Penny Hawken; Irek Malecki; Greg Cozens; Phil Vercoe; Graeme Martin; L.L. Guan

doi:10.1038/srep10372

Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis

Yongjuan Guan, G. Liang, Penny Hawken, Irek Malecki, Greg Cozens, Phil Vercoe, Graeme Martin, L.L. Guan

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

We tested whether reductions in spermatozoal quality induced by under-nutrition are associated with increased germ cell apoptosis and disrupted spermatogenesis, and whether these effects are mediated by small RNAs. Groups of 8 male sheep were fed for a 10% increase or 10% decrease in body mass over 65 days. Underfeeding increased the number of apoptotic germ cells (P

Original language	English
Pages (from-to)	1-14
Journal	Scientific Reports
Volume	5
DOIs	https://doi.org/10.1038/srep10372
Publication status	Published - 2015

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title = "Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis",

abstract = "We tested whether reductions in spermatozoal quality induced by under-nutrition are associated with increased germ cell apoptosis and disrupted spermatogenesis, and whether these effects are mediated by small RNAs. Groups of 8 male sheep were fed for a 10% increase or 10% decrease in body mass over 65 days. Underfeeding increased the number of apoptotic germ cells (P",

author = "Yongjuan Guan and G. Liang and Penny Hawken and Irek Malecki and Greg Cozens and Phil Vercoe and Graeme Martin and L.L. Guan",

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AU - Malecki, Irek

AU - Cozens, Greg

AU - Vercoe, Phil

AU - Martin, Graeme

AU - Guan, L.L.

PY - 2015

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U2 - 10.1038/srep10372

DO - 10.1038/srep10372

M3 - Article

SN - 2045-2322

VL - 5

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JO - Scientific Reports

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Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis

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