Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and a-Terpineol

C.J. Papadopoulos; Christine Carson; Barbara Chang; Thomas Riley

doi:10.1128/AEM.02334-07

Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and a-Terpineol

C.J. Papadopoulos, Christine Carson, Barbara Chang, Thomas Riley

Research output: Contribution to journal › Article › peer-review

81 Citations (Scopus)

Abstract

Using a series of efflux mutants of Pseudomonas aeruginosa, the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and ɑ-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.

Original language	English
Pages (from-to)	1932-1935
Journal	Applied and Environmental Microbiology
Volume	74
Issue number	6
DOIs	https://doi.org/10.1128/AEM.02334-07
Publication status	Published - 2008

Access to Document

10.1128/AEM.02334-07

Cite this

@article{8856db7d6fef41849f4dc63ce4f53f80,

title = "Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and a-Terpineol",

abstract = "Using a series of efflux mutants of Pseudomonas aeruginosa, the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and ɑ-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.",

author = "C.J. Papadopoulos and Christine Carson and Barbara Chang and Thomas Riley",

year = "2008",

doi = "10.1128/AEM.02334-07",

language = "English",

volume = "74",

pages = "1932--1935",

journal = "Applied and Environmental Microbiology",

issn = "0099-2240",

publisher = "American Society for Microbiology",

number = "6",

}

Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and a-Terpineol. / Papadopoulos, C.J.; Carson, Christine ; Chang, Barbara et al.
In: Applied and Environmental Microbiology, Vol. 74, No. 6, 2008, p. 1932-1935.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and a-Terpineol

AU - Papadopoulos, C.J.

AU - Carson, Christine

AU - Chang, Barbara

AU - Riley, Thomas

PY - 2008

Y1 - 2008

N2 - Using a series of efflux mutants of Pseudomonas aeruginosa, the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and ɑ-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.

AB - Using a series of efflux mutants of Pseudomonas aeruginosa, the MexAB-OprM pump was identified as contributing to this organism's tolerance to the antimicrobial agent tea tree (Melaleuca alternifolia) oil and its monoterpene components terpinen-4-ol, 1,8-cineole, and ɑ-terpineol. These data show that a multidrug efflux system of P. aeruginosa can extrude monoterpenes and related alcohols.

U2 - 10.1128/AEM.02334-07

DO - 10.1128/AEM.02334-07

M3 - Article

SN - 0099-2240

VL - 74

SP - 1932

EP - 1935

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 6

ER -

Role of the MexAB-OprM Efflux Pump of Pseudomonas aeruginosa in Tolerance to Tea Tree ( Melaleuca alternifolia ) Oil and Its Monoterpene Components Terpinen-4-ol, 1,8-Cineole, and a-Terpineol

Abstract

Access to Document

Fingerprint

Cite this