Role of integra/surgisis in urinary bladder augmentation: a study in lambs

Parshotam Kumar Gera

    Research output: ThesisMaster's Thesis

    259 Downloads (Pure)


    [Truncated abstract] Management of the small capacity, high-intravesical storage pressure urinary bladder is a major challenge in paediatric and adult urology. Many techniques have been described to simultaneously increase the bladder capacity and decrease the intravesical pressure. Various segments of bowel, ileum, colon and stomach have been used to augment the bladder. Currently, there is no ideal material for bladder augmentation as each one has associated complications. This thesis present our experience with an experimental urinary bladder auto augmentation model using Surgisis® and Integra® (collagen layer) in comparison with seromuscular enterocystoplasty. The aim of the study was to evaluate the change in compliance and elasticity of the urinary bladder. Eighteen lambs were divided into three different groups. Auto augmentation was performed using the seromuscular layer of small bowel, Surgisis® or the collagen layer of Integra®. After 3 months of the initial procedure, the lambs were re-operated, the bladder compliance was measured and the urinary bladder was submitted for histological examination and assessment of elasticity. The lambs were euthanized...
    Original languageEnglish
    Publication statusUnpublished - 2012


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