Abstract
[Truncated abstract] Chronic hepatitis C virus (HCV) infection represents a significant public health problem not only in Australia but also worldwide with approximately 170 million infected individuals and up to 4 million persons infected each year. Unlike hepatitis A or B, there is no vaccination and hence no preventative treatment for HCV. The only option for already HCV-infected individuals is to undergo the HCV combination treatment comprising of Pegylated interferon (Peg-IFN) alfa-2a or alfa-2b in combination with ribavirin (RBV) which is the standard of care (SOC) for HCV treatment approved by the Therapeutic Goods Administration of Australia (TGA). While a number of investigations have shown higher SVR rates with PEG-IFN alfa-2a, but lower relapse rates for Peg-IFN alfa-2b treated subjects with HCV GT 1 (2, 7, 8), limited data exist for the HCV GT 3 infections alone.
| Original language | English |
|---|---|
| Qualification | Masters |
| Publication status | Unpublished - 2014 |
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