Resveratrol: a potential alternative therapeutic agent for patients suffering from chronic obstructive pulmonary disease (COPD)

  • Ong Yan Ren
  • , Yasmeen Siddiqui
  • , Mohammed Tahir Ansari
  • , Asgar Ali

Research output: Contribution to journalReview articlepeer-review

Abstract

This review explores the therapeutic potential of resveratrol, focusing on its molecular and cellular effects on Chronic Obstructive Pulmonary Disease (COPD), bioavailability enhancement strategies, and development challenges for applications in food, pharmaceuticals, and postharvest sectors. Resveratrol protects lungs by activating SIRT1, reducing oxidative stress via ROS regulation through Nrf2-mediated antioxidant enzymes. It shows promise as an alternative to corticosteroids in COPD and cancer treatment. Encapsulation innovations in resveratrol offer opportunities for food fortification, minimizing risks of chemical degradation and isomerization during storage, paving the way for its broader utility in health and nutrition applications.
Original languageEnglish
Pages (from-to)951-965
Number of pages15
JournalJournal of Asian Natural Products Research
Volume27
Issue number7
Early online date10 Mar 2025
DOIs
Publication statusPublished - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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