Respiratory pathogens and morbidity in the first year following very preterm birth: A 12-month prospective cohort study

Nada Townsi

Research output: ThesisDoctoral Thesis

15 Downloads (Pure)

Abstract

This thesis prospectively characterises respiratory morbidity and respiratory pathogens in survivors of very preterm birth, less than 32 weeks' gestation, for one year after hospital discharge using monthly respiratory questionnaire and parent-collected nasal swabs. Very preterm infants, irrespective of neonatal lung disease, experience a high burden of respiratory symptoms with 60.7% having recurrent wheeze (more than 3 episodes) during this time. Respiratory pathogens, most commonly rhinovirus, were readily detected during both symptomatic and asymptomatic assessments. Consequently, prescription of respiratory medications and healthcare utilisation were high. Further research is warranted to determine the long-term impacts of respiratory pathogens on respiratory health later in life.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Award date16 Jun 2019
DOIs
Publication statusUnpublished - 2019

Fingerprint

Infant, Newborn, Diseases
Rhinovirus
compound A 12
Premature Birth
Nose
Premature Infants
Lung Diseases
Prescriptions
Survivors
Cohort Studies
Prospective Studies
Morbidity
Delivery of Health Care
Pregnancy
Health
Research
Surveys and Questionnaires

Cite this

@phdthesis{57a63ec314564713b0ec81cb194fa651,
title = "Respiratory pathogens and morbidity in the first year following very preterm birth: A 12-month prospective cohort study",
abstract = "This thesis prospectively characterises respiratory morbidity and respiratory pathogens in survivors of very preterm birth, less than 32 weeks' gestation, for one year after hospital discharge using monthly respiratory questionnaire and parent-collected nasal swabs. Very preterm infants, irrespective of neonatal lung disease, experience a high burden of respiratory symptoms with 60.7{\%} having recurrent wheeze (more than 3 episodes) during this time. Respiratory pathogens, most commonly rhinovirus, were readily detected during both symptomatic and asymptomatic assessments. Consequently, prescription of respiratory medications and healthcare utilisation were high. Further research is warranted to determine the long-term impacts of respiratory pathogens on respiratory health later in life.",
keywords = "Preterm infants, respiratory, Respiratory viruses, first year",
author = "Nada Townsi",
year = "2019",
doi = "10.26182/5d268263ca6ee",
language = "English",
school = "The University of Western Australia",

}

TY - THES

T1 - Respiratory pathogens and morbidity in the first year following very preterm birth: A 12-month prospective cohort study

AU - Townsi, Nada

PY - 2019

Y1 - 2019

N2 - This thesis prospectively characterises respiratory morbidity and respiratory pathogens in survivors of very preterm birth, less than 32 weeks' gestation, for one year after hospital discharge using monthly respiratory questionnaire and parent-collected nasal swabs. Very preterm infants, irrespective of neonatal lung disease, experience a high burden of respiratory symptoms with 60.7% having recurrent wheeze (more than 3 episodes) during this time. Respiratory pathogens, most commonly rhinovirus, were readily detected during both symptomatic and asymptomatic assessments. Consequently, prescription of respiratory medications and healthcare utilisation were high. Further research is warranted to determine the long-term impacts of respiratory pathogens on respiratory health later in life.

AB - This thesis prospectively characterises respiratory morbidity and respiratory pathogens in survivors of very preterm birth, less than 32 weeks' gestation, for one year after hospital discharge using monthly respiratory questionnaire and parent-collected nasal swabs. Very preterm infants, irrespective of neonatal lung disease, experience a high burden of respiratory symptoms with 60.7% having recurrent wheeze (more than 3 episodes) during this time. Respiratory pathogens, most commonly rhinovirus, were readily detected during both symptomatic and asymptomatic assessments. Consequently, prescription of respiratory medications and healthcare utilisation were high. Further research is warranted to determine the long-term impacts of respiratory pathogens on respiratory health later in life.

KW - Preterm infants

KW - respiratory

KW - Respiratory viruses

KW - first year

U2 - 10.26182/5d268263ca6ee

DO - 10.26182/5d268263ca6ee

M3 - Doctoral Thesis

ER -