Resistant Hypertension: Which Agent?

Hamish C.G. Prosser, Omar Azzam, Markus P. Schlaich

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Resistant hypertension is commonly defined as office blood pressure above recommended target despite the use of optimal doses of at least three antihypertensive drugs including a diuretic. Australian guidelines recommend combination of blockers of the renin-angiotensin system, either ACE inhibitors or angiotensin receptor blockers, with calcium channel blockers and diuretics as the preferred triple therapy. A substantial proportion of hypertensive patients will require additional pharmacotherapy to achieve or get close to target blood pressure levels. Here we briefly review the evidence currently available to provide guidance on the most appropriate choice for additional antihypertensive pharmacotherapy and touch on interventional approaches that may be considered in some patients.

Original languageEnglish
Pages (from-to)911-916
Number of pages6
JournalHeart Lung and Circulation
Volume27
Issue number8
DOIs
Publication statusPublished - 1 Aug 2018

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