Projects per year
Abstract
Omega-6 (ω6) and omega-3 (ω3) fatty acids are two classes of dietary polyunsaturated fatty acids derived from linoleic acid (18:2ω6) and α-linolenic acid (18:3ω3), respectively. Enzymatic metabolism of linoleic and α-linolenic acids generates arachidonic acid (20:4ω6) and eicosapentaenoic acid (20:5ω3; EPA), respectively, both of which are substrates for enzymes that yield eicosanoids with multiple and varying physiological functions. Further elongation and desaturation of EPA yields the 22-carbon fatty acid docosahexaenoic acid (22:6ω3; DHA). The main dietary source of EPA and DHA for human consumption is fish, especially oily fish. There is considerable evidence that EPA and DHA are protective against cardiovascular disease (heart disease and stroke), particularly in individuals with pre-existing disease. ω3 Fatty acids benefit multiple risk factors including blood pressure, blood vessel function, heart function and blood lipids, and they have antithrombotic, anti-inflammatory and anti-oxidative actions. ω3 Fatty acids do not adversely interact with medications. Supplementation with ω3 fatty acids is recommended in individuals with elevated blood triglyceride levels and patients with coronary heart disease. A practical recommendation for the general population is to increase ω3 fatty acid intake by incorporating fish as part of a healthy diet that includes increased fruits and vegetables, and moderation of salt intake. Health authorities recommend the general population should consume at least two oily fish meals per week.
Original language | English |
---|---|
Pages (from-to) | 8-15 |
Number of pages | 8 |
Journal | Fitoterapia |
Volume | 126 |
DOIs | |
Publication status | Published - 1 Apr 2018 |
Fingerprint
Dive into the research topics of 'Reprint of: Marine OMEGA-3 fatty acids in the prevention of cardiovascular disease'. Together they form a unique fingerprint.Projects
- 4 Finished
-
NHMRC Research Fellowships - Trevor Mori
Mori, T. (Investigator 01)
NHMRC National Health and Medical Research Council
1/01/13 → 31/12/17
Project: Research
-
Effects of Omega-3 fatty Acids and Coenzyme Q10 on Cardiovascular Risk in Chronic Renal Failure
Mori, T. (Chief Investigator), Watts, G. (Chief Investigator), Puddey, I. (Chief Investigator), Irish, A. (Chief Investigator) & Beilin, L. (Chief Investigator)
1/01/04 → 31/12/06
Project: Research
-
A health promotion program incorporating fish for withdrawal of antihypertensive drugs in overweight, hypertensives
Beilin, L. (Chief Investigator), Burke, V. (Chief Investigator) & Mori, T. (Chief Investigator)
1/01/00 → 31/12/03
Project: Research