Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference

Emily Y. Gan; Viktoria Eleftheriadou; Samia Esmat; Iltefat Hamzavi; Thierry Passeron; Markus Böhm; Tag Anbar; Boon Kee Goh; Cheng Che E Lan; Harvey Lui; M. Ramam; Noufal Raboobee; Ichiro Katayama; Tamio Suzuki; Davinder Parsad; Vaneeta Seth; Henry W. Lim; Nanja van Geel; Sanjeev Mulekar; John Harris; Richard Wittal; Laila Benzekri; Yvon Gauthier; Prasad Kumarasinghe; Steven T G Thng; Caio Cesar Silva de Castro; Marwa Abdallah; Charlotte Vrijman; Marcel Bekkenk; Julien Seneschal; Amit G. Pandya; Khaled Ezzedine; Mauro Picardo; Alain Taïeb; the VGICC

doi:10.1111/pcmr.12561

Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference

Emily Y. Gan, Viktoria Eleftheriadou, Samia Esmat, Iltefat Hamzavi, Thierry Passeron, Markus Böhm, Tag Anbar, Boon Kee Goh, Cheng Che E Lan, Harvey Lui, M. Ramam, Noufal Raboobee, Ichiro Katayama, Tamio Suzuki, Davinder Parsad, Vaneeta Seth, Henry W. Lim, Nanja van Geel, Sanjeev Mulekar, John HarrisRichard Wittal, Laila Benzekri, Yvon Gauthier, Prasad Kumarasinghe, Steven T G Thng, Caio Cesar Silva de Castro, Marwa Abdallah, Charlotte Vrijman, Marcel Bekkenk, Julien Seneschal, Amit G. Pandya, Khaled Ezzedine, Mauro Picardo, Alain Taïeb, the VGICC

UWA Medical School

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that ‘repigmentation’ and ‘maintenance of gained repigmentation’ are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.

Original language	English
Pages (from-to)	28-40
Number of pages	13
Journal	Pigment Cell and Melanoma Research
Volume	30
Issue number	1
DOIs	https://doi.org/10.1111/pcmr.12561
Publication status	Published - 1 Jan 2017

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10.1111/pcmr.12561

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Gan, E. Y., Eleftheriadou, V., Esmat, S., Hamzavi, I., Passeron, T., Böhm, M., Anbar, T., Goh, B. K., Lan, C. C. E., Lui, H., Ramam, M., Raboobee, N., Katayama, I., Suzuki, T., Parsad, D., Seth, V., Lim, H. W., van Geel, N., Mulekar, S., ... the VGICC (2017). Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference. Pigment Cell and Melanoma Research, 30(1), 28-40. https://doi.org/10.1111/pcmr.12561

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title = "Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference",

abstract = "The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that {\textquoteleft}repigmentation{\textquoteright} and {\textquoteleft}maintenance of gained repigmentation{\textquoteright} are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.",

keywords = "outcome measure, pigment, repigmentation, repigmentation pattern, vitiligo",

author = "Gan, {Emily Y.} and Viktoria Eleftheriadou and Samia Esmat and Iltefat Hamzavi and Thierry Passeron and Markus B{\"o}hm and Tag Anbar and Goh, {Boon Kee} and Lan, {Cheng Che E} and Harvey Lui and M. Ramam and Noufal Raboobee and Ichiro Katayama and Tamio Suzuki and Davinder Parsad and Vaneeta Seth and Lim, {Henry W.} and {van Geel}, Nanja and Sanjeev Mulekar and John Harris and Richard Wittal and Laila Benzekri and Yvon Gauthier and Prasad Kumarasinghe and Thng, {Steven T G} and {Silva de Castro}, {Caio Cesar} and Marwa Abdallah and Charlotte Vrijman and Marcel Bekkenk and Julien Seneschal and Pandya, {Amit G.} and Khaled Ezzedine and Mauro Picardo and Alain Ta{\"i}eb and {the VGICC}",

year = "2017",

month = jan,

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doi = "10.1111/pcmr.12561",

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journal = "Pigment Cell and Melanoma Research",

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Gan, EY, Eleftheriadou, V, Esmat, S, Hamzavi, I, Passeron, T, Böhm, M, Anbar, T, Goh, BK, Lan, CCE, Lui, H, Ramam, M, Raboobee, N, Katayama, I, Suzuki, T, Parsad, D, Seth, V, Lim, HW, van Geel, N, Mulekar, S, Harris, J, Wittal, R, Benzekri, L, Gauthier, Y, Kumarasinghe, P, Thng, STG, Silva de Castro, CC, Abdallah, M, Vrijman, C, Bekkenk, M, Seneschal, J, Pandya, AG, Ezzedine, K, Picardo, M, Taïeb, A & the VGICC 2017, 'Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference', Pigment Cell and Melanoma Research, vol. 30, no. 1, pp. 28-40. https://doi.org/10.1111/pcmr.12561

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T1 - Repigmentation in vitiligo

T2 - position paper of the Vitiligo Global Issues Consensus Conference

AU - Gan, Emily Y.

AU - Eleftheriadou, Viktoria

AU - Esmat, Samia

AU - Hamzavi, Iltefat

AU - Passeron, Thierry

AU - Böhm, Markus

AU - Anbar, Tag

AU - Goh, Boon Kee

AU - Lan, Cheng Che E

AU - Lui, Harvey

AU - Ramam, M.

AU - Raboobee, Noufal

AU - Katayama, Ichiro

AU - Suzuki, Tamio

AU - Parsad, Davinder

AU - Seth, Vaneeta

AU - Lim, Henry W.

AU - van Geel, Nanja

AU - Mulekar, Sanjeev

AU - Harris, John

AU - Wittal, Richard

AU - Benzekri, Laila

AU - Gauthier, Yvon

AU - Kumarasinghe, Prasad

AU - Thng, Steven T G

AU - Silva de Castro, Caio Cesar

AU - Abdallah, Marwa

AU - Vrijman, Charlotte

AU - Bekkenk, Marcel

AU - Seneschal, Julien

AU - Pandya, Amit G.

AU - Ezzedine, Khaled

AU - Picardo, Mauro

AU - Taïeb, Alain

AU - the VGICC

PY - 2017/1/1

Y1 - 2017/1/1

N2 - The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that ‘repigmentation’ and ‘maintenance of gained repigmentation’ are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.

AB - The Vitiligo Global Issues Consensus Conference (VGICC), through an international e-Delphi consensus, concluded that ‘repigmentation’ and ‘maintenance of gained repigmentation’ are essential core outcome measures in future vitiligo trials. This VGICC position paper addresses these core topics in two sections and includes an atlas depicting vitiligo repigmentation patterns and color match. The first section delineates mechanisms and characteristics of vitiligo repigmentation, and the second section summarizes the outcomes of international meeting discussions and two e-surveys on vitiligo repigmentation, which had been carried out over 3 yr. Treatment is defined as successful if repigmentation exceeds 80% and at least 80% of the gained repigmentation is maintained for over 6 months. No agreement was found on the best outcome measure for assessing target or global repigmentation, therefore highlighting the limitations of e-surveys in addressing clinical measurements. Until there is a clear consensus, existing tools should be selected according to the specific needs of each study. A workshop will be conducted to address the remaining issues so as to achieve a consensus.

KW - outcome measure

KW - pigment

KW - repigmentation

KW - repigmentation pattern

KW - vitiligo

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U2 - 10.1111/pcmr.12561

DO - 10.1111/pcmr.12561

M3 - Article

C2 - 27864868

AN - SCOPUS:85010911725

SN - 1755-1471

VL - 30

SP - 28

EP - 40

JO - Pigment Cell and Melanoma Research

JF - Pigment Cell and Melanoma Research

IS - 1

ER -

Repigmentation in vitiligo: position paper of the Vitiligo Global Issues Consensus Conference

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