Renal cell carcinoma to haemangioblastoma metastasis: A rare manifestation of von Hippel-Lindau syndrome

Benjamin F. Dessauvagie, G. Wong, P. D. Robbins

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Brain metastases are the most common intracranial malignancy in adults and may occasionally deposit within a pre-existing primary brain neoplasm. We describe, in two directly related family members, the rare occurrence of renal cell carcinoma (RCC) metastasis to haemangioblastoma (HB) in the context of Von Hippel-Lindau syndrome. Detection of this phenomenon can be marred by histological overlap between RCC and HB and therefore careful histological examination, and consideration of supportive immunohistochemistry, is required when examining all HB resections. Metastatic RCC to HB upstages a primary RCC and is clinically diagnostic of Von Hippel-Lindau syndrome.

Original languageEnglish
Pages (from-to)215-218
Number of pages4
JournalJournal of Clinical Neuroscience
Volume22
Issue number1
DOIs
Publication statusPublished - 1 Jan 2015
Externally publishedYes

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