Remineralizing potential of ClinPro ® and tooth mousse plus ® on artificial carious lesions

Sakshi Buckshey, Robert P. Anthonappa, Nigel M. King, Anut Itthagarun

Research output: Contribution to journalArticle

Abstract

Background: Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization. Aim: To evaluate and compare (i) the remineralizing potential of Clinpro ® Tooth Crème(CTC) and Tooth Mousse Plus ® (TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP. Study design: Carious lesions, 200-300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100-150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Results: Post-treatment maximum mineral content at the surface zone(Vmax) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance. Conclusions: CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.

Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalJournal of Clinical Pediatric Dentistry
Volume43
Issue number2
DOIs
Publication statusPublished - 1 Jan 2019

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Dentifrices
Tooth
Minerals
Microradiography
Dental Enamel
Fluorides
casein phosphopeptide-amorphous calcium phosphate nanocomplex
Microscopy
Light

Cite this

@article{8cf2e409131d4bca8bf46bd41debf0c9,
title = "Remineralizing potential of ClinPro {\circledR} and tooth mousse plus {\circledR} on artificial carious lesions",
abstract = "Background: Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization. Aim: To evaluate and compare (i) the remineralizing potential of Clinpro {\circledR} Tooth Cr{\`e}me(CTC) and Tooth Mousse Plus {\circledR} (TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP. Study design: Carious lesions, 200-300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100-150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Results: Post-treatment maximum mineral content at the surface zone(Vmax) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance. Conclusions: CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.",
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author = "Sakshi Buckshey and Anthonappa, {Robert P.} and King, {Nigel M.} and Anut Itthagarun",
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Remineralizing potential of ClinPro ® and tooth mousse plus ® on artificial carious lesions. / Buckshey, Sakshi; Anthonappa, Robert P.; King, Nigel M.; Itthagarun, Anut.

In: Journal of Clinical Pediatric Dentistry, Vol. 43, No. 2, 01.01.2019, p. 103-108.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Remineralizing potential of ClinPro ® and tooth mousse plus ® on artificial carious lesions

AU - Buckshey, Sakshi

AU - Anthonappa, Robert P.

AU - King, Nigel M.

AU - Itthagarun, Anut

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization. Aim: To evaluate and compare (i) the remineralizing potential of Clinpro ® Tooth Crème(CTC) and Tooth Mousse Plus ® (TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP. Study design: Carious lesions, 200-300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100-150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Results: Post-treatment maximum mineral content at the surface zone(Vmax) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance. Conclusions: CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.

AB - Background: Calcium phosphate and fluoride (F) delivery systems claim to facilitate enamel remineralization. Aim: To evaluate and compare (i) the remineralizing potential of Clinpro ® Tooth Crème(CTC) and Tooth Mousse Plus ® (TMP) on artificial carious lesions, and (ii) the benefit of 1000ppm F dentifrice prior to the application of CTC and TMP. Study design: Carious lesions, 200-300μm deep were produced by placing molars in demineralizing solution for 96h, sections 100-150μm thick were then randomly assigned to six groups(n=150). Specimens were treated thrice daily with a non-fluoridated(Group A), or fluoridated dentifrice[1000ppm, (Group B)], or CTC(Group C), TMP(Group D), fluoridated dentifrice followed by CTC(Group E), or a fluoridated dentifrice followed by TMP(Group F), and then subjected to a 10-day pH cycling model. Lesion evaluation involved polarizing light microscopy and microradiography. Results: Post-treatment maximum mineral content at the surface zone(Vmax) was significantly increased in Groups B, C, and D compared to the other groups. The lesion depth(LD) decreased in Group D>Group C>Group E, and the net mineral content gain(ΔZ) in Group C>Group D, which did not reach statistical significance. Conclusions: CTC and TMP exhibited similar efficacy in remineralizing artificial carious lesions. Nevertheless, the net mineral gain or lesion consolidation following CTC use was higher than TMP.

KW - Clinpro

KW - Remineralization

KW - Tooth Mousse Plus

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U2 - 10.17796/1053-4625-43.2.6

DO - 10.17796/1053-4625-43.2.6

M3 - Article

VL - 43

SP - 103

EP - 108

JO - Journal of Clinical Pediatric Dentistry

JF - Journal of Clinical Pediatric Dentistry

SN - 0145-5508

IS - 2

ER -