TY - JOUR
T1 - Relationships between plasma concentrations of leptin and other metabolic hormones in GH-transgenic sheep infused with glucose
AU - Kadokawa, H.
AU - Briegel, J.R.
AU - Blackberry, Margaret
AU - Blache, Dominique
AU - Martin, Graeme
AU - Adams, N.R.
PY - 2003
Y1 - 2003
N2 - To study the regulation of leptin secretion in sheep, we infused glucose (0.32 g/h/kg for 12 h) intoGH-transgenic animals (n = 8) that have chronically high plasma concentrations of ovine GH andinsulin, but low body condition and low plasma leptin concentrations, and compared the responseswith those in controls (n = 8). In both groups, the infusion increased plasma concentrations ofglucose and insulin within 1 h and maintained high levels throughout the infusion period (P
AB - To study the regulation of leptin secretion in sheep, we infused glucose (0.32 g/h/kg for 12 h) intoGH-transgenic animals (n = 8) that have chronically high plasma concentrations of ovine GH andinsulin, but low body condition and low plasma leptin concentrations, and compared the responseswith those in controls (n = 8). In both groups, the infusion increased plasma concentrations ofglucose and insulin within 1 h and maintained high levels throughout the infusion period (P
U2 - 10.1016/S0739-7240(03)00039-0
DO - 10.1016/S0739-7240(03)00039-0
M3 - Article
VL - 24
SP - 219
EP - 229
JO - Domestic Animal Endocrinology
JF - Domestic Animal Endocrinology
SN - 0739-7240
IS - 3
ER -