TY - JOUR
T1 - Relationships among body composition, circulating concentrations of leptin and follistatin, and the onset of puberty and fertility in young female sheep
AU - Rosales Nieto, Cesar
AU - Thompson, A.N.
AU - Macleay, C.A.
AU - Briegel, J.R.
AU - Hedger, M.P.
AU - Ferguson, M.B.
AU - Martin, Graeme
PY - 2014
Y1 - 2014
N2 - © 2014 Elsevier B.V. The onset of puberty depends on the attainment of critical body mass, so should also be affected by increases in the rate of accumulation of muscle and adipose tissue. Adipose tissue and reproduction are linked by leptin. For muscle, a link has not yet been identified, although one possibility is follistatin. We assessed the relationships among circulating concentrations of follistatin and leptin and the rates of growth and accumulation of muscle and fat during pubertal development in female sheep. We used 326 animals with known phenotypic values for live weight (LW), depths of eye muscle (EMD) and fat (FAT), and known breeding values at post-weaning age for body mass (PWT) and depths of eye muscle (PEMD) and fat (PFAT). Leptin concentration was positively correlated with values for EMD, PEMD, FAT, PFAT, LW and PWT (P
AB - © 2014 Elsevier B.V. The onset of puberty depends on the attainment of critical body mass, so should also be affected by increases in the rate of accumulation of muscle and adipose tissue. Adipose tissue and reproduction are linked by leptin. For muscle, a link has not yet been identified, although one possibility is follistatin. We assessed the relationships among circulating concentrations of follistatin and leptin and the rates of growth and accumulation of muscle and fat during pubertal development in female sheep. We used 326 animals with known phenotypic values for live weight (LW), depths of eye muscle (EMD) and fat (FAT), and known breeding values at post-weaning age for body mass (PWT) and depths of eye muscle (PEMD) and fat (PFAT). Leptin concentration was positively correlated with values for EMD, PEMD, FAT, PFAT, LW and PWT (P
U2 - 10.1016/j.anireprosci.2014.10.008
DO - 10.1016/j.anireprosci.2014.10.008
M3 - Article
C2 - 25458319
VL - 151
SP - 148
EP - 156
JO - Animal Reproduction Science
JF - Animal Reproduction Science
SN - 0378-4320
IS - 3-4
ER -