Regular brief interruptions to sitting after a high-energy evening meal attenuate glycemic excursions in overweight/obese adults

R. E. Climie, M. S. Grace, R. L. Larsen, P. C. Dempsey, J. Oberoi, N. D. Cohen, N. Owen, B. A. Kingwell, D. W. Dunstan

Research output: Contribution to journalArticle

11 Citations (Scopus)
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Abstract

Background and aims: Modern Western lifestyles are characterized by consumption of approximately 45% of total daily energy intake at the evening meal, followed by prolonged sitting while watching television (TV), which may deleteriously impact glycemic control. After a high-energy evening meal (dinner), we examined whether regular, brief activity bouts during TV commercial breaks could acutely lower postprandial glucose and insulin responses in overweight/obese adults, compared to prolonged uninterrupted sitting. Methods and results: Nine overweight/obese adults (29.7 ± 4.06 kg m−2; aged 32 ± 3 years; 5 male) completed two laboratory-based conditions of three and a half hours: prolonged sitting during TV viewing (SIT); and, prolonged sitting interrupted every 20 min with 3 min of light-intensity body-weight resistance activities (active commercial breaks; ACBs). Venous postprandial glucose and insulin responses to dinner were calculated as positive incremental area under the curve (iAUC) from baseline. Interstitial glucose was measured using a continuous glucose monitor and quantified as total AUC (tAUC). Compared to SIT, plasma glucose iAUC was reduced by 33% [3.4 ± 1.0 vs 5.1 ± 1.0 (mean ± SEM) mmol h·L−1, p = 0.019] and plasma insulin iAUC by 41% (813 ± 224 vs 1373 ± 224, p = 0.033 pmol h·L−1) for the ACB condition. During the ACB condition there was a significant reduction in interstitial glucose tAUC (24.4 ± 5.2 vs 26.9 ± 5.2 mmol h·L−1, p < 0.001), but this did not persist beyond the laboratory observation period. Conclusions: Regular brief light-intensity activity bouts can attenuate glycemic responses during television viewing time following a high-energy evening meal in overweight/obese adults.

Original languageEnglish
Pages (from-to)909-916
Number of pages8
JournalNutrition, Metabolism and Cardiovascular Diseases
Volume28
Issue number9
DOIs
Publication statusPublished - 1 Sep 2018

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