Abstract
Patients presenting with acute coronary syndrome (ACS) carry a significant risk of future major adverse cardiovascular events (MACE), despite the use of existing risk stratification tools and advancement in available therapies. This has led to the need for improvement in the existing risk stratification tools.
Optical coherence tomography (OCT) is a light based, intravascular imaging modality with the ability to characterise atherosclerotic plaque with a high resolution that approaches to that of histology. Existing data suggests that presence of high risk plaque features potentially provides prognostic information in patients with ACS. This doctoral thesis focuses on refining the methodology of plaque analysis and evaluating the potential role of OCT in risk stratification of patients with ACS.
Optical coherence tomography (OCT) is a light based, intravascular imaging modality with the ability to characterise atherosclerotic plaque with a high resolution that approaches to that of histology. Existing data suggests that presence of high risk plaque features potentially provides prognostic information in patients with ACS. This doctoral thesis focuses on refining the methodology of plaque analysis and evaluating the potential role of OCT in risk stratification of patients with ACS.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Award date | 27 Apr 2021 |
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| Publication status | Unpublished - 2021 |