Reductive changes to polynuclear iron (III) clusters in iron-loaded human spleen tissue

W. Chua-Anusorn, Tim St Pierre, D.J. Macey, J. Webb

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    Mossbauer spectroscopy was used to monitor, over a period of three days, the form of iron in iron-loaded spleen tissue following splenectomy from a patient with beta-thalassemia. The tissue was stored at room temperature for a three day period in order to allow degradation and autolytic processes to take place. The majority of the iron in the fresh spleen tissue was found to be in the form of inorganic polynuclear iron(III) oxyhydroxide clusters associated with ferritin and hemosiderin. After three days, some of the iron had been reduced to high-spin iron(II). (C) 1998 Elsevier Science S.A.
    Original languageEnglish
    Pages (from-to)7-10
    JournalInorganica Chimica Acta
    Volume267
    Issue numberN/A
    DOIs
    Publication statusPublished - 1998

    Fingerprint

    spleen
    Iron
    Tissue
    iron
    Hemosiderin
    Mossbauer spectroscopy
    Ferritins
    Degradation
    degradation
    room temperature
    spectroscopy
    Temperature

    Cite this

    Chua-Anusorn, W. ; St Pierre, Tim ; Macey, D.J. ; Webb, J. / Reductive changes to polynuclear iron (III) clusters in iron-loaded human spleen tissue. In: Inorganica Chimica Acta. 1998 ; Vol. 267, No. N/A. pp. 7-10.
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    abstract = "Mossbauer spectroscopy was used to monitor, over a period of three days, the form of iron in iron-loaded spleen tissue following splenectomy from a patient with beta-thalassemia. The tissue was stored at room temperature for a three day period in order to allow degradation and autolytic processes to take place. The majority of the iron in the fresh spleen tissue was found to be in the form of inorganic polynuclear iron(III) oxyhydroxide clusters associated with ferritin and hemosiderin. After three days, some of the iron had been reduced to high-spin iron(II). (C) 1998 Elsevier Science S.A.",
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    Reductive changes to polynuclear iron (III) clusters in iron-loaded human spleen tissue. / Chua-Anusorn, W.; St Pierre, Tim; Macey, D.J.; Webb, J.

    In: Inorganica Chimica Acta, Vol. 267, No. N/A, 1998, p. 7-10.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Reductive changes to polynuclear iron (III) clusters in iron-loaded human spleen tissue

    AU - Chua-Anusorn, W.

    AU - St Pierre, Tim

    AU - Macey, D.J.

    AU - Webb, J.

    PY - 1998

    Y1 - 1998

    N2 - Mossbauer spectroscopy was used to monitor, over a period of three days, the form of iron in iron-loaded spleen tissue following splenectomy from a patient with beta-thalassemia. The tissue was stored at room temperature for a three day period in order to allow degradation and autolytic processes to take place. The majority of the iron in the fresh spleen tissue was found to be in the form of inorganic polynuclear iron(III) oxyhydroxide clusters associated with ferritin and hemosiderin. After three days, some of the iron had been reduced to high-spin iron(II). (C) 1998 Elsevier Science S.A.

    AB - Mossbauer spectroscopy was used to monitor, over a period of three days, the form of iron in iron-loaded spleen tissue following splenectomy from a patient with beta-thalassemia. The tissue was stored at room temperature for a three day period in order to allow degradation and autolytic processes to take place. The majority of the iron in the fresh spleen tissue was found to be in the form of inorganic polynuclear iron(III) oxyhydroxide clusters associated with ferritin and hemosiderin. After three days, some of the iron had been reduced to high-spin iron(II). (C) 1998 Elsevier Science S.A.

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    DO - 10.1016/S0020-1693(97)05542-4

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    JO - Inorganica Chemica Acta

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