Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease

T.H. Johnston; S.H. Fox; M. Mcildowie; Matthew Piggott; J.M. Brotchie

doi:10.1124/jpet.110.166629

Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease

T.H. Johnston, S.H. Fox, M. Mcildowie, Matthew Piggott, J.M. Brotchie

School of Molecular Sciences

Research output: Contribution to journal › Article › peer-review

122 Citations (Scopus)

Original language	English
Pages (from-to)	865-873
Journal	The Journal of Pharmacology and Experimental Therapeutics
Volume	333
Issue number	3
DOIs	https://doi.org/10.1124/jpet.110.166629
Publication status	Published - 2010

Access to Document

10.1124/jpet.110.166629

Cite this

Johnston, T. H., Fox, S. H., Mcildowie, M., Piggott, M., & Brotchie, J. M. (2010). Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics, 333(3), 865-873. https://doi.org/10.1124/jpet.110.166629

Johnston, T.H. ; Fox, S.H. ; Mcildowie, M. et al. / Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. In: The Journal of Pharmacology and Experimental Therapeutics. 2010 ; Vol. 333, No. 3. pp. 865-873.

@article{cabdc93744014890be0a63c2b7b6dc4d,

title = "Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease",

author = "T.H. Johnston and S.H. Fox and M. Mcildowie and Matthew Piggott and J.M. Brotchie",

year = "2010",

doi = "10.1124/jpet.110.166629",

language = "English",

volume = "333",

pages = "865--873",

journal = "The Journal of Pharmacology and Experimental Therapeutics",

issn = "0022-3565",

publisher = "American Society for Pharmacology and Experimental Therapeutics",

number = "3",

}

Johnston, TH, Fox, SH, Mcildowie, M, Piggott, M & Brotchie, JM 2010, 'Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease', The Journal of Pharmacology and Experimental Therapeutics, vol. 333, no. 3, pp. 865-873. https://doi.org/10.1124/jpet.110.166629

Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. / Johnston, T.H.; Fox, S.H.; Mcildowie, M. et al.

In: The Journal of Pharmacology and Experimental Therapeutics, Vol. 333, No. 3, 2010, p. 865-873.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease

AU - Johnston, T.H.

AU - Fox, S.H.

AU - Mcildowie, M.

AU - Piggott, Matthew

AU - Brotchie, J.M.

PY - 2010

Y1 - 2010

U2 - 10.1124/jpet.110.166629

DO - 10.1124/jpet.110.166629

M3 - Article

C2 - 20231306

VL - 333

SP - 865

EP - 873

JO - The Journal of Pharmacology and Experimental Therapeutics

JF - The Journal of Pharmacology and Experimental Therapeutics

SN - 0022-3565

IS - 3

ER -

Johnston TH, Fox SH, Mcildowie M, Piggott M, Brotchie JM. Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 2010;333(3):865-873. https://doi.org/10.1124/jpet.110.166629