Reduction in Staphylococcus aureus bacteraemia rates in patients receiving haemodialysis following alteration of skin antisepsis procedures

B.J. Stewart; T. Gardiner; Gregory Perry; S.Y.C. Tong

doi:10.1016/j.jhin.2015.10.022

Reduction in Staphylococcus aureus bacteraemia rates in patients receiving haemodialysis following alteration of skin antisepsis procedures

B.J. Stewart, T. Gardiner, Gregory Perry, S.Y.C. Tong

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

This study examined all cases of Staphylococcus aureus bacteraemia (SAB) in the haemodialysis cohort at the Royal Darwin Hospital, Australia over a seven-year period. Midway through this period, antisepsis for arteriovenous fistulae (AVF) and central venous catheters (CVC) changed from 0.5% chlorhexidine solution to 2% chlorhexidine solution. Rates of SAB episodes were calculated using registry data. Trends in SAB over time were analysed using an interrupted regression analysis. Following the change to 2% chlorhexidine, average SAB rates decreased by 68%, and it is estimated that 0.111 cases of SAB/patient-year were prevented. CVC-related SAB rates remained low throughout. These results support the use of 2% chlorhexidine in skin antisepsis for patients with AVF.
© 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	191-193
Number of pages	3
Journal	Journal of Hospital Infection
Volume	92
Issue number	2
Early online date	1 Dec 2015
DOIs	https://doi.org/10.1016/j.jhin.2015.10.022
Publication status	Published - 1 Feb 2016
Externally published	Yes

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title = "Reduction in Staphylococcus aureus bacteraemia rates in patients receiving haemodialysis following alteration of skin antisepsis procedures",

abstract = "This study examined all cases of Staphylococcus aureus bacteraemia (SAB) in the haemodialysis cohort at the Royal Darwin Hospital, Australia over a seven-year period. Midway through this period, antisepsis for arteriovenous fistulae (AVF) and central venous catheters (CVC) changed from 0.5\% chlorhexidine solution to 2\% chlorhexidine solution. Rates of SAB episodes were calculated using registry data. Trends in SAB over time were analysed using an interrupted regression analysis. Following the change to 2\% chlorhexidine, average SAB rates decreased by 68\%, and it is estimated that 0.111 cases of SAB/patient-year were prevented. CVC-related SAB rates remained low throughout. These results support the use of 2\% chlorhexidine in skin antisepsis for patients with AVF. {\textcopyright} 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.",

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AU - Stewart, B.J.

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AU - Perry, Gregory

AU - Tong, S.Y.C.

PY - 2016/2/1

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AB - This study examined all cases of Staphylococcus aureus bacteraemia (SAB) in the haemodialysis cohort at the Royal Darwin Hospital, Australia over a seven-year period. Midway through this period, antisepsis for arteriovenous fistulae (AVF) and central venous catheters (CVC) changed from 0.5% chlorhexidine solution to 2% chlorhexidine solution. Rates of SAB episodes were calculated using registry data. Trends in SAB over time were analysed using an interrupted regression analysis. Following the change to 2% chlorhexidine, average SAB rates decreased by 68%, and it is estimated that 0.111 cases of SAB/patient-year were prevented. CVC-related SAB rates remained low throughout. These results support the use of 2% chlorhexidine in skin antisepsis for patients with AVF. © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

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Reduction in Staphylococcus aureus bacteraemia rates in patients receiving haemodialysis following alteration of skin antisepsis procedures

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