Reducing depression during the menopausal transition with health coaching: Results from the healthy menopausal transition randomised controlled trial

Osvaldo P. Almeida, Kylie Marsh, Karen Murray, Martha Hickey, Moira Sim, Andrew Ford, Leon Flicker

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective To determine if health coaching (HC) decreases the incidence of depression, reduces the severity of symptoms, and increases quality of life during the menopausal transition (MT). Research design and methods Parallel, single-blinded, randomised controlled trial of 6 sessions of phone-delivered HC compared with usual care. Participants were 351 community-dwelling women free of major depression going through the MT, of whom 180 were assigned the intervention and 171 usual care. The primary outcome of interest was the incidence of clinically significant depressive symptoms over 52 weeks. Other study measures included the Hospital Anxiety and Depression Scale, quality of life (SF-12), the Menopause Rating Scale (MRS), diet, body mass index, alcohol use, smoking and physical activity. We considered that women with Patient Health Questionnaire (PHQ-9) scores between 5 and 14 (inclusive) had sub-threshold depressive symptoms. Results Nine women developed clinically significant symptoms of depression during the study—2 had been assigned HC (odds ratio, OR = 0.26, 95%CI = 0.05, 1.29; p = 0.099). Intention-to-treat showed that, compared with usual care, the intervention led to a greater decline in depressive scores, most markedly for participants with sub-threshold depressive symptoms. Similar, but less pronounced, benefits were noticed for anxiety scores and the mental component summary of the SF-12. The intervention led to a decline in MRS scores by week 26 and subtle improvements in body mass, consumption of vegetables and smoking. Conclusions HC addressing relevant risk factors for depression during the MT improves mental health measures. Our findings indicate that women with sub-threshold depressive symptoms may benefit the most from such interventions, and suggest that HC could play a useful role in minimizing mental health disturbance for women going through the MT.

Original languageEnglish
Pages (from-to)41-48
Number of pages8
JournalMaturitas
Volume92
DOIs
Publication statusPublished - 1 Oct 2016

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Health Transition
Randomized Controlled Trials
Health
Depression
Menopause
Mental Health
Anxiety
Smoking
Quality of Life
Independent Living
Mentoring
Vegetables
Nutrition
Incidence
Alcohols
Body Mass Index
Research Design
Odds Ratio
Exercise
Diet

Cite this

@article{56496154609644a49305daf900b97b46,
title = "Reducing depression during the menopausal transition with health coaching: Results from the healthy menopausal transition randomised controlled trial",
abstract = "Objective To determine if health coaching (HC) decreases the incidence of depression, reduces the severity of symptoms, and increases quality of life during the menopausal transition (MT). Research design and methods Parallel, single-blinded, randomised controlled trial of 6 sessions of phone-delivered HC compared with usual care. Participants were 351 community-dwelling women free of major depression going through the MT, of whom 180 were assigned the intervention and 171 usual care. The primary outcome of interest was the incidence of clinically significant depressive symptoms over 52 weeks. Other study measures included the Hospital Anxiety and Depression Scale, quality of life (SF-12), the Menopause Rating Scale (MRS), diet, body mass index, alcohol use, smoking and physical activity. We considered that women with Patient Health Questionnaire (PHQ-9) scores between 5 and 14 (inclusive) had sub-threshold depressive symptoms. Results Nine women developed clinically significant symptoms of depression during the study—2 had been assigned HC (odds ratio, OR = 0.26, 95{\%}CI = 0.05, 1.29; p = 0.099). Intention-to-treat showed that, compared with usual care, the intervention led to a greater decline in depressive scores, most markedly for participants with sub-threshold depressive symptoms. Similar, but less pronounced, benefits were noticed for anxiety scores and the mental component summary of the SF-12. The intervention led to a decline in MRS scores by week 26 and subtle improvements in body mass, consumption of vegetables and smoking. Conclusions HC addressing relevant risk factors for depression during the MT improves mental health measures. Our findings indicate that women with sub-threshold depressive symptoms may benefit the most from such interventions, and suggest that HC could play a useful role in minimizing mental health disturbance for women going through the MT.",
keywords = "Depression, Depressive disorder, Health coaching, Major depression, Menopausal transition, Perimenopause, Randomised controlled trial",
author = "Almeida, {Osvaldo P.} and Kylie Marsh and Karen Murray and Martha Hickey and Moira Sim and Andrew Ford and Leon Flicker",
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Reducing depression during the menopausal transition with health coaching : Results from the healthy menopausal transition randomised controlled trial. / Almeida, Osvaldo P.; Marsh, Kylie; Murray, Karen; Hickey, Martha; Sim, Moira; Ford, Andrew; Flicker, Leon.

In: Maturitas, Vol. 92, 01.10.2016, p. 41-48.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Reducing depression during the menopausal transition with health coaching

T2 - Results from the healthy menopausal transition randomised controlled trial

AU - Almeida, Osvaldo P.

AU - Marsh, Kylie

AU - Murray, Karen

AU - Hickey, Martha

AU - Sim, Moira

AU - Ford, Andrew

AU - Flicker, Leon

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Objective To determine if health coaching (HC) decreases the incidence of depression, reduces the severity of symptoms, and increases quality of life during the menopausal transition (MT). Research design and methods Parallel, single-blinded, randomised controlled trial of 6 sessions of phone-delivered HC compared with usual care. Participants were 351 community-dwelling women free of major depression going through the MT, of whom 180 were assigned the intervention and 171 usual care. The primary outcome of interest was the incidence of clinically significant depressive symptoms over 52 weeks. Other study measures included the Hospital Anxiety and Depression Scale, quality of life (SF-12), the Menopause Rating Scale (MRS), diet, body mass index, alcohol use, smoking and physical activity. We considered that women with Patient Health Questionnaire (PHQ-9) scores between 5 and 14 (inclusive) had sub-threshold depressive symptoms. Results Nine women developed clinically significant symptoms of depression during the study—2 had been assigned HC (odds ratio, OR = 0.26, 95%CI = 0.05, 1.29; p = 0.099). Intention-to-treat showed that, compared with usual care, the intervention led to a greater decline in depressive scores, most markedly for participants with sub-threshold depressive symptoms. Similar, but less pronounced, benefits were noticed for anxiety scores and the mental component summary of the SF-12. The intervention led to a decline in MRS scores by week 26 and subtle improvements in body mass, consumption of vegetables and smoking. Conclusions HC addressing relevant risk factors for depression during the MT improves mental health measures. Our findings indicate that women with sub-threshold depressive symptoms may benefit the most from such interventions, and suggest that HC could play a useful role in minimizing mental health disturbance for women going through the MT.

AB - Objective To determine if health coaching (HC) decreases the incidence of depression, reduces the severity of symptoms, and increases quality of life during the menopausal transition (MT). Research design and methods Parallel, single-blinded, randomised controlled trial of 6 sessions of phone-delivered HC compared with usual care. Participants were 351 community-dwelling women free of major depression going through the MT, of whom 180 were assigned the intervention and 171 usual care. The primary outcome of interest was the incidence of clinically significant depressive symptoms over 52 weeks. Other study measures included the Hospital Anxiety and Depression Scale, quality of life (SF-12), the Menopause Rating Scale (MRS), diet, body mass index, alcohol use, smoking and physical activity. We considered that women with Patient Health Questionnaire (PHQ-9) scores between 5 and 14 (inclusive) had sub-threshold depressive symptoms. Results Nine women developed clinically significant symptoms of depression during the study—2 had been assigned HC (odds ratio, OR = 0.26, 95%CI = 0.05, 1.29; p = 0.099). Intention-to-treat showed that, compared with usual care, the intervention led to a greater decline in depressive scores, most markedly for participants with sub-threshold depressive symptoms. Similar, but less pronounced, benefits were noticed for anxiety scores and the mental component summary of the SF-12. The intervention led to a decline in MRS scores by week 26 and subtle improvements in body mass, consumption of vegetables and smoking. Conclusions HC addressing relevant risk factors for depression during the MT improves mental health measures. Our findings indicate that women with sub-threshold depressive symptoms may benefit the most from such interventions, and suggest that HC could play a useful role in minimizing mental health disturbance for women going through the MT.

KW - Depression

KW - Depressive disorder

KW - Health coaching

KW - Major depression

KW - Menopausal transition

KW - Perimenopause

KW - Randomised controlled trial

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DO - 10.1016/j.maturitas.2016.07.012

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