Recent Therapeutic Progress and Future Perspectives for the Treatment of Hearing Loss

Joey Lye, Derek S. Delaney, Fiona K. Leith, Varda S. Sardesai, Samuel McLenachan, Fred K. Chen, Marcus D. Atlas, Elaine Y.M. Wong

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Up to 1.5 billion people worldwide suffer from various forms of hearing loss, with an additional 1.1 billion people at risk from various insults such as increased consumption of recreational noise-emitting devices and ageing. The most common type of hearing impairment is sensorineural hearing loss caused by the degeneration or malfunction of cochlear hair cells or spiral ganglion nerves in the inner ear. There is currently no cure for hearing loss. However, emerging frontier technologies such as gene, drug or cell-based therapies offer hope for an effective cure. In this review, we discuss the current therapeutic progress for the treatment of hearing loss. We describe and evaluate the major therapeutic approaches being applied to hearing loss and summarize the key trials and studies.

Original languageEnglish
Article number3347
JournalBiomedicines
Volume11
Issue number12
DOIs
Publication statusPublished - Dec 2023

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