TY - JOUR
T1 - Recent progress in the structure of glycogen serving as a durable energy reserve in bacteria
AU - Wang, Liang
AU - Wang, Mengmeng
AU - Wise, Michael J.
AU - Liu, Qinghua
AU - Yang, Ting
AU - Zhu, Zuobin
AU - Li, Chengcheng
AU - Tan, Xinle
AU - Tang, Daoquan
AU - Wang, Wei
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Glycogen is conventionally considered as a transient energy reserve that can be rapidly synthesized for glucose accumulation and mobilized for ATP production. However, this conception is not completely applicable to prokaryotes due to glycogen structural heterogeneity. A number of studies noticed that glycogen with small average chain length gc in bacteria has the potential to degrade slowly, which might prolong bacterial environment survival. This phenomenon was previously examined and later formulated as the durable energy storage mechanism hypothesis. Although recent research has been warming to the hypothesis, experimental validation is still missing at current stage. In this review, we summarized recent progress of the hypothesis, provided a supporting mathematical model, and explored the technical pitfalls that shall be avoided in glycogen study.
AB - Glycogen is conventionally considered as a transient energy reserve that can be rapidly synthesized for glucose accumulation and mobilized for ATP production. However, this conception is not completely applicable to prokaryotes due to glycogen structural heterogeneity. A number of studies noticed that glycogen with small average chain length gc in bacteria has the potential to degrade slowly, which might prolong bacterial environment survival. This phenomenon was previously examined and later formulated as the durable energy storage mechanism hypothesis. Although recent research has been warming to the hypothesis, experimental validation is still missing at current stage. In this review, we summarized recent progress of the hypothesis, provided a supporting mathematical model, and explored the technical pitfalls that shall be avoided in glycogen study.
KW - Average chain length
KW - Degradation
KW - Environmental persistence
KW - Glycogen
KW - Size exclusion chromatography
KW - β Particle
UR - http://www.scopus.com/inward/record.url?scp=85077201073&partnerID=8YFLogxK
U2 - 10.1007/s11274-019-2795-6
DO - 10.1007/s11274-019-2795-6
M3 - Review article
C2 - 31897771
AN - SCOPUS:85077201073
SN - 0959-3993
VL - 36
JO - World Journal of Microbiology and Biotechnology
JF - World Journal of Microbiology and Biotechnology
IS - 1
M1 - 14
ER -