Reactions of electron-rich indoles with triflic anhydride

N.R. Yepuri, R. Haritakul, P.A. Keller, Brian Skelton, Allan White

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


The reaction of electron-rich 3-aryl-substituted 4,6-dimethoxyindoles in the presence of base with triflic anhydride results in biaryl coupling, producing both 2,2′- and 2,7′-biindoles. Further, if acetone is present, the corresponding vinyl triflate is formed and subsequent reaction yields the known indolylpyrroloindoles and dimeric spiroindoles. This is the first reported synthesis of these compounds under basic conditions.
Original languageEnglish
Pages (from-to)2501-2504
JournalTetrahedron Letters
Issue number21
Publication statusPublished - 2009


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