Rate of Nonsurveillance and Advanced Hepatocellular Carcinoma at Diagnosis in Chronic Liver Disease

Yi Huang, Michael C. Wallace, Leon A. Adams, Gerry MacQuillan, George Garas, John Ferguson, Shaun Samuelson, Jonathan Tibballs, Gary P. Jeffrey

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5 Citations (Scopus)


Aims:Ultrasound surveillance for hepatocellular carcinoma (HCC) is recommended in cirrhotic patients to allow early diagnosis. This study investigated risk factors for nonsurveillance and advanced HCC at diagnosis and their effect on survival.Materials and Methods:Two hundred seventy HCC patients were included. Clinical data were collected from hospital databases.Results:One hundred twenty-eight (47.1%) patients had 6-monthly ultrasound surveillance before HCC diagnosis. Ninety-two (34.1%) patients had advanced HCC (multifocal or total diameter 6cm) at diagnosis. The nonsurveillance rate was significantly higher in nonalcoholic fatty liver disease (NAFLD) (79%) compared with other causes of chronic liver disease (31.6% to 58.1%, P

Original languageEnglish
Pages (from-to)551-556
Number of pages6
JournalJournal of Clinical Gastroenterology
Issue number6
Publication statusPublished - Jul 2018

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