Rapid measurement of urease activity using a potentiometric RuO2 pH sensor for detection of Helicobacter pylori

W. Lonsdale, D. K. Maurya, M. Wajrak, C. Y. Tay, B. J. Marshall, K. Alameh

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The feasibility of using a thin-film RuO2 (ruthenium oxide) pH sensor for the detection of Helicobacter pylori is investigated. In particular, we demonstrate the ability of the sensor to measure urease activity between 1.0 and 50 U/mL in less than 30 s. The developed sensor exhibited a super-Nernstian response of 77.74 mV/pH and excellent reversibility. The pH sensor⿿s ability to detect H. pylori in real time is demonstrated, and found to be much faster than the rapid urease test.

Original languageEnglish
Pages (from-to)1305-1308
Number of pages4
JournalSensors and Actuators, B: Chemical
Volume242
DOIs
Publication statusPublished - 1 Apr 2017

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