Quantifying the influence of Bessel beams on image quality in optical coherence tomography

Andrea Curatolo, Peter Munro, Dirk Lorenser, P. Sreekumar, C.C. Singe, Brendan Kennedy, David Sampson

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)
193 Downloads (Pure)

Abstract

Light scattered by turbid tissue is known to degrade optical coherence tomography (OCT) image contrast progressively with depth. Bessel beams have been proposed as an alternative to Gaussian beams to image deeper into turbid tissue. However, studies of turbid tissue comparing the image quality for different beam types are lacking. We present such a study, using numerically simulated beams and experimental OCT images formed by Bessel or Gaussian beams illuminating phantoms with optical properties spanning a range typical of soft tissue. We demonstrate that, for a given scattering parameter, the higher the scattering anisotropy the lower the OCT contrast, regardless of the beam type. When focusing both beams at the same depth in the sample, we show that, at focus and for equal input power and resolution, imaging with the Gaussian beam suffers less reduction of contrast. This suggests that, whilst Bessel beams offer extended depth of field in a single depth scan, for low numerical aperture (NA <0.1) and typical soft tissue properties (scattering coefficient, Î 1/4 s = 3.7 mm â ˆ'1 and high scattering anisotropy, g > 0.95), superior contrast (by up to ~40%) may be obtained over an extended depth range by a Gaussian beam combined with dynamic focusing.
Original languageEnglish
Article number23483
Pages (from-to)1-12
JournalScientific Reports
Volume6
DOIs
Publication statusPublished - 24 Mar 2016

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