Quantification of retinal oxygen consumption changes from preretinal oxygen transients

Stephen Cringle, Dao-Yi Yu, V.A. Alder, Er-Ning Su, Paula Yu

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Background: In the avascular retina of the guinea-pig ail the oxygen supply is from the choroid. Under these circumstances we had proposed, on theoretical grounds, that a change in retinal oxygen consumption would modulate the preretinal oxygen level.Methods: in the present study in guinea-pigs, the oxygen consumption of-the outer retina was modulated by light-dark exposure while preretinal oxygen tension was monitored.Results: The results were in complete agreement with the proposed mathematical models.Conclusion: The present study demonstrates that it is feasible to quantify oxygen consumption changes in a known retinal layer from measurements of preretinal oxygen tension.
Original languageEnglish
Pages (from-to)S71-S73
JournalAustralian and New Zealand Journal of Ophthalmology
Volume26 (Suppl.)
DOIs
Publication statusPublished - 1998

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