Abstract
This study analysed the intracellular delivery capacity of insect derived pyrrhocoricin with a peptide cargo in Cryptosporidium parvum in vitro using fluorescence microscopy. Results revealed that pyrrhocoricin was capable of acting as a delivery vehicle in transducing peptides across the parasite cell membrane for multiple life-cycle stages. The successful transduction may aid in target validation and the delivery of future peptide-based drugs against this important human pathogen.
Original language | English |
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Pages (from-to) | 301-303 |
Journal | Experimental Parasitology |
Volume | 119 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2008 |