Pyroglyphid house dust mite allergens

Wayne Thomas, Tatjana Heinrich, Wendy-Anne Smith, Belinda Hales

Research output: Contribution to journalArticlepeer-review

52 Citations (Scopus)

Abstract

Mites of the family Pyroglyphidae are the most important source of house dust mite allergens. A small number of allergens, namely those of groups 1, 2, 4, 5 and 7 constitute the known major and mid-potency specificities, with possible important contributions of the groups 11, 14 and 15 requiring further definition. Most of the allergens can be identified by sequence homologies and the structures of the major allergens have been solved. There are however challenges in determining the nature of the group 5 and 7 allergens and in obtaining detailed structures of the significant allergens to be used for genetic engineering
Original languageEnglish
Pages (from-to)943-953
JournalProtein and Peptide Letters
Volume14
DOIs
Publication statusPublished - 2007

Fingerprint

Dive into the research topics of 'Pyroglyphid house dust mite allergens'. Together they form a unique fingerprint.

Cite this