TY - JOUR
T1 - Pyroglyphid house dust mite allergens
AU - Thomas, Wayne
AU - Heinrich, Tatjana
AU - Smith, Wendy-Anne
AU - Hales, Belinda
PY - 2007
Y1 - 2007
N2 - Mites of the family Pyroglyphidae are the most important source of house dust mite allergens. A small number of allergens, namely those of groups 1, 2, 4, 5 and 7 constitute the known major and mid-potency specificities, with possible important contributions of the groups 11, 14 and 15 requiring further definition. Most of the allergens can be identified by sequence homologies and the structures of the major allergens have been solved. There are however challenges in determining the nature of the group 5 and 7 allergens and in obtaining detailed structures of the significant allergens to be used for genetic engineering
AB - Mites of the family Pyroglyphidae are the most important source of house dust mite allergens. A small number of allergens, namely those of groups 1, 2, 4, 5 and 7 constitute the known major and mid-potency specificities, with possible important contributions of the groups 11, 14 and 15 requiring further definition. Most of the allergens can be identified by sequence homologies and the structures of the major allergens have been solved. There are however challenges in determining the nature of the group 5 and 7 allergens and in obtaining detailed structures of the significant allergens to be used for genetic engineering
U2 - 10.2174/092986607782541169
DO - 10.2174/092986607782541169
M3 - Article
SN - 0929-8665
VL - 14
SP - 943
EP - 953
JO - Protein and Peptide Letters
JF - Protein and Peptide Letters
ER -