Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

E.J. Rossin; K. Lage; S. Raychaudhuri; R.J. Xavier; D. Tatar; Y. Benita; Ian Lawrance; C. Cotsapas; M.J. Daly; A. Franke; D.P.B. Mcgovern; J.C. Barrett; K Wang; G.L. Radford-Smith; T Ahmad; C.W. Lees; T. Balschun; J. Lee; R. Roberts; C.A. Anderson; J.C. Bis; S. Bumpstead; D. Ellinghaus; E.M. Festen; M. Georges; T. Haritunians; L. Jostins; A. Latiano; C.G. Mathew; G.W. Montgomery; N.J. Prescott; J.I. Rotter; P. Schumm; Y. Sharma; L.A. Simms; K.D. Taylor; D. Whiteman; C. Wijmenga; R.N. Baldassano; M. Barclay; T.M. Bayless; S. Brand; C. Bunning; A. Cohen; J-F. Colombel; M. Cottone; L. Stronati; T. Denson; M. De Vos; R. D'Inca; M. Dubinsky; C. Edwards; T. Florin; D. Franchimont; R. Gearry; J. Glas; A. Van Gossum; S.L. Guthery; J. Halfvarson; D. Hommes; J-P. Hugot; D. Laukens; M. Lemann; A. Levine; C. Libioulle; E. Louis; C. Mowat; W. Newman; J. Panes; A. Phillips; D.D. Proctor; M. Regueiro; P. Rutgeerts; J. Sanderson; M. Sans; F. Seibold; A.H. Steinhart; P.C.F. Stokkers; L. Torkvist; G. Kullak-Ublick; T. Walters; S.R. Targan; S.R. Brant; J.D. Rioux; M. D'Amato; R. Weersma; S. Kutharthasan; A.M. Griffiths; J.C. Mansfield; S. Vermeire; R.H. Duerr; M.S. Silverberg; J. Satsangi; S. Schreiber; J.H. Cho; V. Annese; H. Hakonarson; M. Parkes

doi:10.1371/journal.pgen.1001273

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

E.J. Rossin, K. Lage, S. Raychaudhuri, R.J. Xavier, D. Tatar, Y. Benita, Ian Lawrance, C. Cotsapas, M.J. Daly, A. Franke, D.P.B. Mcgovern, J.C. Barrett, K Wang, G.L. Radford-Smith, T Ahmad, C.W. Lees, T. Balschun, J. Lee, R. Roberts, C.A. AndersonJ.C. Bis, S. Bumpstead, D. Ellinghaus, E.M. Festen, M. Georges, T. Haritunians, L. Jostins, A. Latiano, C.G. Mathew, G.W. Montgomery, N.J. Prescott, J.I. Rotter, P. Schumm, Y. Sharma, L.A. Simms, K.D. Taylor, D. Whiteman, C. Wijmenga, R.N. Baldassano, M. Barclay, T.M. Bayless, S. Brand, C. Bunning, A. Cohen, J-F. Colombel, M. Cottone, L. Stronati, T. Denson, M. De Vos, R. D'Inca, M. Dubinsky, C. Edwards, T. Florin, D. Franchimont, R. Gearry, J. Glas, A. Van Gossum, S.L. Guthery, J. Halfvarson, D. Hommes, J-P. Hugot, D. Laukens, M. Lemann, A. Levine, C. Libioulle, E. Louis, C. Mowat, W. Newman, J. Panes, A. Phillips, D.D. Proctor, M. Regueiro, P. Rutgeerts, J. Sanderson, M. Sans, F. Seibold, A.H. Steinhart, P.C.F. Stokkers, L. Torkvist, G. Kullak-Ublick, T. Walters, S.R. Targan, S.R. Brant, J.D. Rioux, M. D'Amato, R. Weersma, S. Kutharthasan, A.M. Griffiths, J.C. Mansfield, S. Vermeire, R.H. Duerr, M.S. Silverberg, J. Satsangi, S. Schreiber, J.H. Cho, V. Annese, H. Hakonarson, M. Parkes

Research output: Contribution to journal › Article › peer-review

364 Citations (Scopus)

Original language	English
Pages (from-to)	13pp
Journal	PLoS Genetics
Volume	7
Issue number	1
DOIs	https://doi.org/10.1371/journal.pgen.1001273
Publication status	Published - 2011

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10.1371/journal.pgen.1001273

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Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., ... Parkes, M. (2011). Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology. PLoS Genetics, 7(1), 13pp. https://doi.org/10.1371/journal.pgen.1001273

Rossin, E.J. ; Lage, K. ; Raychaudhuri, S. ; Xavier, R.J. ; Tatar, D. ; Benita, Y. ; Lawrance, Ian ; Cotsapas, C. ; Daly, M.J. ; Franke, A. ; Mcgovern, D.P.B. ; Barrett, J.C. ; Wang, K ; Radford-Smith, G.L. ; Ahmad, T ; Lees, C.W. ; Balschun, T. ; Lee, J. ; Roberts, R. ; Anderson, C.A. ; Bis, J.C. ; Bumpstead, S. ; Ellinghaus, D. ; Festen, E.M. ; Georges, M. ; Haritunians, T. ; Jostins, L. ; Latiano, A. ; Mathew, C.G. ; Montgomery, G.W. ; Prescott, N.J. ; Rotter, J.I. ; Schumm, P. ; Sharma, Y. ; Simms, L.A. ; Taylor, K.D. ; Whiteman, D. ; Wijmenga, C. ; Baldassano, R.N. ; Barclay, M. ; Bayless, T.M. ; Brand, S. ; Bunning, C. ; Cohen, A. ; Colombel, J-F. ; Cottone, M. ; Stronati, L. ; Denson, T. ; De Vos, M. ; D'Inca, R. ; Dubinsky, M. ; Edwards, C. ; Florin, T. ; Franchimont, D. ; Gearry, R. ; Glas, J. ; Van Gossum, A. ; Guthery, S.L. ; Halfvarson, J. ; Hommes, D. ; Hugot, J-P. ; Laukens, D. ; Lemann, M. ; Levine, A. ; Libioulle, C. ; Louis, E. ; Mowat, C. ; Newman, W. ; Panes, J. ; Phillips, A. ; Proctor, D.D. ; Regueiro, M. ; Rutgeerts, P. ; Sanderson, J. ; Sans, M. ; Seibold, F. ; Steinhart, A.H. ; Stokkers, P.C.F. ; Torkvist, L. ; Kullak-Ublick, G. ; Walters, T. ; Targan, S.R. ; Brant, S.R. ; Rioux, J.D. ; D'Amato, M. ; Weersma, R. ; Kutharthasan, S. ; Griffiths, A.M. ; Mansfield, J.C. ; Vermeire, S. ; Duerr, R.H. ; Silverberg, M.S. ; Satsangi, J. ; Schreiber, S. ; Cho, J.H. ; Annese, V. ; Hakonarson, H. ; Parkes, M. / Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology. In: PLoS Genetics. 2011 ; Vol. 7, No. 1. pp. 13pp.

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title = "Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology",

author = "E.J. Rossin and K. Lage and S. Raychaudhuri and R.J. Xavier and D. Tatar and Y. Benita and Ian Lawrance and C. Cotsapas and M.J. Daly and A. Franke and D.P.B. Mcgovern and J.C. Barrett and K Wang and G.L. Radford-Smith and T Ahmad and C.W. Lees and T. Balschun and J. Lee and R. Roberts and C.A. Anderson and J.C. Bis and S. Bumpstead and D. Ellinghaus and E.M. Festen and M. Georges and T. Haritunians and L. Jostins and A. Latiano and C.G. Mathew and G.W. Montgomery and N.J. Prescott and J.I. Rotter and P. Schumm and Y. Sharma and L.A. Simms and K.D. Taylor and D. Whiteman and C. Wijmenga and R.N. Baldassano and M. Barclay and T.M. Bayless and S. Brand and C. Bunning and A. Cohen and J-F. Colombel and M. Cottone and L. Stronati and T. Denson and {De Vos}, M. and R. D'Inca and M. Dubinsky and C. Edwards and T. Florin and D. Franchimont and R. Gearry and J. Glas and {Van Gossum}, A. and S.L. Guthery and J. Halfvarson and D. Hommes and J-P. Hugot and D. Laukens and M. Lemann and A. Levine and C. Libioulle and E. Louis and C. Mowat and W. Newman and J. Panes and A. Phillips and D.D. Proctor and M. Regueiro and P. Rutgeerts and J. Sanderson and M. Sans and F. Seibold and A.H. Steinhart and P.C.F. Stokkers and L. Torkvist and G. Kullak-Ublick and T. Walters and S.R. Targan and S.R. Brant and J.D. Rioux and M. D'Amato and R. Weersma and S. Kutharthasan and A.M. Griffiths and J.C. Mansfield and S. Vermeire and R.H. Duerr and M.S. Silverberg and J. Satsangi and S. Schreiber and J.H. Cho and V. Annese and H. Hakonarson and M. Parkes",

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doi = "10.1371/journal.pgen.1001273",

language = "English",

volume = "7",

pages = "13pp",

journal = "PLoS Genetics",

issn = "1553-7390",

publisher = "Public Library of Science (PLoS)",

number = "1",

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Rossin, EJ, Lage, K, Raychaudhuri, S, Xavier, RJ, Tatar, D, Benita, Y, Lawrance, I, Cotsapas, C, Daly, MJ, Franke, A, Mcgovern, DPB, Barrett, JC, Wang, K, Radford-Smith, GL, Ahmad, T, Lees, CW, Balschun, T, Lee, J, Roberts, R, Anderson, CA, Bis, JC, Bumpstead, S, Ellinghaus, D, Festen, EM, Georges, M, Haritunians, T, Jostins, L, Latiano, A, Mathew, CG, Montgomery, GW, Prescott, NJ, Rotter, JI, Schumm, P, Sharma, Y, Simms, LA, Taylor, KD, Whiteman, D, Wijmenga, C, Baldassano, RN, Barclay, M, Bayless, TM, Brand, S, Bunning, C, Cohen, A, Colombel, J-F, Cottone, M, Stronati, L, Denson, T, De Vos, M, D'Inca, R, Dubinsky, M, Edwards, C, Florin, T, Franchimont, D, Gearry, R, Glas, J, Van Gossum, A, Guthery, SL, Halfvarson, J, Hommes, D, Hugot, J-P, Laukens, D, Lemann, M, Levine, A, Libioulle, C, Louis, E, Mowat, C, Newman, W, Panes, J, Phillips, A, Proctor, DD, Regueiro, M, Rutgeerts, P, Sanderson, J, Sans, M, Seibold, F, Steinhart, AH, Stokkers, PCF, Torkvist, L, Kullak-Ublick, G, Walters, T, Targan, SR, Brant, SR, Rioux, JD, D'Amato, M, Weersma, R, Kutharthasan, S, Griffiths, AM, Mansfield, JC, Vermeire, S, Duerr, RH, Silverberg, MS, Satsangi, J, Schreiber, S, Cho, JH, Annese, V, Hakonarson, H & Parkes, M 2011, 'Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology', PLoS Genetics, vol. 7, no. 1, pp. 13pp. https://doi.org/10.1371/journal.pgen.1001273

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology. / Rossin, E.J.; Lage, K.; Raychaudhuri, S.; Xavier, R.J.; Tatar, D.; Benita, Y.; Lawrance, Ian; Cotsapas, C.; Daly, M.J.; Franke, A.; Mcgovern, D.P.B.; Barrett, J.C.; Wang, K; Radford-Smith, G.L.; Ahmad, T; Lees, C.W.; Balschun, T.; Lee, J.; Roberts, R.; Anderson, C.A.; Bis, J.C.; Bumpstead, S.; Ellinghaus, D.; Festen, E.M.; Georges, M.; Haritunians, T.; Jostins, L.; Latiano, A.; Mathew, C.G.; Montgomery, G.W.; Prescott, N.J.; Rotter, J.I.; Schumm, P.; Sharma, Y.; Simms, L.A.; Taylor, K.D.; Whiteman, D.; Wijmenga, C.; Baldassano, R.N.; Barclay, M.; Bayless, T.M.; Brand, S.; Bunning, C.; Cohen, A.; Colombel, J-F.; Cottone, M.; Stronati, L.; Denson, T.; De Vos, M.; D'Inca, R.; Dubinsky, M.; Edwards, C.; Florin, T.; Franchimont, D.; Gearry, R.; Glas, J.; Van Gossum, A.; Guthery, S.L.; Halfvarson, J.; Hommes, D.; Hugot, J-P.; Laukens, D.; Lemann, M.; Levine, A.; Libioulle, C.; Louis, E.; Mowat, C.; Newman, W.; Panes, J.; Phillips, A.; Proctor, D.D.; Regueiro, M.; Rutgeerts, P.; Sanderson, J.; Sans, M.; Seibold, F.; Steinhart, A.H.; Stokkers, P.C.F.; Torkvist, L.; Kullak-Ublick, G.; Walters, T.; Targan, S.R.; Brant, S.R.; Rioux, J.D.; D'Amato, M.; Weersma, R.; Kutharthasan, S.; Griffiths, A.M.; Mansfield, J.C.; Vermeire, S.; Duerr, R.H.; Silverberg, M.S.; Satsangi, J.; Schreiber, S.; Cho, J.H.; Annese, V.; Hakonarson, H.; Parkes, M.

In: PLoS Genetics, Vol. 7, No. 1, 2011, p. 13pp.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

AU - Rossin, E.J.

AU - Lage, K.

AU - Raychaudhuri, S.

AU - Xavier, R.J.

AU - Tatar, D.

AU - Benita, Y.

AU - Lawrance, Ian

AU - Cotsapas, C.

AU - Daly, M.J.

AU - Franke, A.

AU - Mcgovern, D.P.B.

AU - Barrett, J.C.

AU - Wang, K

AU - Radford-Smith, G.L.

AU - Ahmad, T

AU - Lees, C.W.

AU - Balschun, T.

AU - Lee, J.

AU - Roberts, R.

AU - Anderson, C.A.

AU - Bis, J.C.

AU - Bumpstead, S.

AU - Ellinghaus, D.

AU - Festen, E.M.

AU - Georges, M.

AU - Haritunians, T.

AU - Jostins, L.

AU - Latiano, A.

AU - Mathew, C.G.

AU - Montgomery, G.W.

AU - Prescott, N.J.

AU - Rotter, J.I.

AU - Schumm, P.

AU - Sharma, Y.

AU - Simms, L.A.

AU - Taylor, K.D.

AU - Whiteman, D.

AU - Wijmenga, C.

AU - Baldassano, R.N.

AU - Barclay, M.

AU - Bayless, T.M.

AU - Brand, S.

AU - Bunning, C.

AU - Cohen, A.

AU - Colombel, J-F.

AU - Cottone, M.

AU - Stronati, L.

AU - Denson, T.

AU - De Vos, M.

AU - D'Inca, R.

AU - Dubinsky, M.

AU - Edwards, C.

AU - Florin, T.

AU - Franchimont, D.

AU - Gearry, R.

AU - Glas, J.

AU - Van Gossum, A.

AU - Guthery, S.L.

AU - Halfvarson, J.

AU - Hommes, D.

AU - Hugot, J-P.

AU - Laukens, D.

AU - Lemann, M.

AU - Levine, A.

AU - Libioulle, C.

AU - Louis, E.

AU - Mowat, C.

AU - Newman, W.

AU - Panes, J.

AU - Phillips, A.

AU - Proctor, D.D.

AU - Regueiro, M.

AU - Rutgeerts, P.

AU - Sanderson, J.

AU - Sans, M.

AU - Seibold, F.

AU - Steinhart, A.H.

AU - Stokkers, P.C.F.

AU - Torkvist, L.

AU - Kullak-Ublick, G.

AU - Walters, T.

AU - Targan, S.R.

AU - Brant, S.R.

AU - Rioux, J.D.

AU - D'Amato, M.

AU - Weersma, R.

AU - Kutharthasan, S.

AU - Griffiths, A.M.

AU - Mansfield, J.C.

AU - Vermeire, S.

AU - Duerr, R.H.

AU - Silverberg, M.S.

AU - Satsangi, J.

AU - Schreiber, S.

AU - Cho, J.H.

AU - Annese, V.

AU - Hakonarson, H.

AU - Parkes, M.

PY - 2011

Y1 - 2011

U2 - 10.1371/journal.pgen.1001273

DO - 10.1371/journal.pgen.1001273

M3 - Article

C2 - 21249183

VL - 7

SP - 13pp

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 1

ER -