Protein consumption is an important predictor of lower limb bone mass in elderly women

A. Devine, Ian Dick, A.F.M. Islam, S.S. Dhaliwal, Richard Prince

Research output: Contribution to journalArticle

75 Citations (Scopus)

Abstract

BACKGROUND:: The effect of protein intake on bone density is uncertain, and evidence exists for beneficial effects of both low and high protein intakes.OBJECTIVE:: The objective was to study the relation between protein consumption and bone mass in elderly women with allowance for other lifestyle factors affecting bone metabolism.DESIGN:: We conducted a cross-sectional and longitudinal study of a population-based sample of 1077 women aged 75 ± 3 y. At baseline, protein consumption was measured with a food-frequency questionnaire, and bone mass and structure were measured by using quantitative ultrasound of the heel. One year later, hip bone mineral density (BMD) was measured by using dual-energy X-ray absorptiometry.RESULTS:: Subjects consumed a mean (±SD) of 80.5 ± 27.8 g protein/d (1.19 ± 0.44 g protein/kg body wt). Regression analysis showed a positive correlation between protein intake and qualitative ultrasound of the heel and BMD after adjustment for age, body mass index, and other nutrients. The dose-response effect was best characterized by protein consumption expressed in tertiles, such that subjects in the lowest tertile (87 g protein/d).CONCLUSION:: These data suggest that protein intakes for elderly women above current recommendations may be necessary to optimize bone mass.
Original languageEnglish
Pages (from-to)1423-1428
JournalAmerican Journal of Clinical Nutrition
Volume81
Issue number6
Publication statusPublished - 2005

Fingerprint

Lower Extremity
Bone and Bones
Proteins
Bone Density
Pelvic Bones
Food
Calcaneus
Heel
Photon Absorptiometry
Longitudinal Studies
Life Style
Body Mass Index
Cross-Sectional Studies
Regression Analysis
Population

Cite this

@article{04ad96dc567b47be8c1a052c8654d22e,
title = "Protein consumption is an important predictor of lower limb bone mass in elderly women",
abstract = "BACKGROUND:: The effect of protein intake on bone density is uncertain, and evidence exists for beneficial effects of both low and high protein intakes.OBJECTIVE:: The objective was to study the relation between protein consumption and bone mass in elderly women with allowance for other lifestyle factors affecting bone metabolism.DESIGN:: We conducted a cross-sectional and longitudinal study of a population-based sample of 1077 women aged 75 ± 3 y. At baseline, protein consumption was measured with a food-frequency questionnaire, and bone mass and structure were measured by using quantitative ultrasound of the heel. One year later, hip bone mineral density (BMD) was measured by using dual-energy X-ray absorptiometry.RESULTS:: Subjects consumed a mean (±SD) of 80.5 ± 27.8 g protein/d (1.19 ± 0.44 g protein/kg body wt). Regression analysis showed a positive correlation between protein intake and qualitative ultrasound of the heel and BMD after adjustment for age, body mass index, and other nutrients. The dose-response effect was best characterized by protein consumption expressed in tertiles, such that subjects in the lowest tertile (87 g protein/d).CONCLUSION:: These data suggest that protein intakes for elderly women above current recommendations may be necessary to optimize bone mass.",
author = "A. Devine and Ian Dick and A.F.M. Islam and S.S. Dhaliwal and Richard Prince",
year = "2005",
language = "English",
volume = "81",
pages = "1423--1428",
journal = "The American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "6",

}

Protein consumption is an important predictor of lower limb bone mass in elderly women. / Devine, A.; Dick, Ian; Islam, A.F.M.; Dhaliwal, S.S.; Prince, Richard.

In: American Journal of Clinical Nutrition, Vol. 81, No. 6, 2005, p. 1423-1428.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Protein consumption is an important predictor of lower limb bone mass in elderly women

AU - Devine, A.

AU - Dick, Ian

AU - Islam, A.F.M.

AU - Dhaliwal, S.S.

AU - Prince, Richard

PY - 2005

Y1 - 2005

N2 - BACKGROUND:: The effect of protein intake on bone density is uncertain, and evidence exists for beneficial effects of both low and high protein intakes.OBJECTIVE:: The objective was to study the relation between protein consumption and bone mass in elderly women with allowance for other lifestyle factors affecting bone metabolism.DESIGN:: We conducted a cross-sectional and longitudinal study of a population-based sample of 1077 women aged 75 ± 3 y. At baseline, protein consumption was measured with a food-frequency questionnaire, and bone mass and structure were measured by using quantitative ultrasound of the heel. One year later, hip bone mineral density (BMD) was measured by using dual-energy X-ray absorptiometry.RESULTS:: Subjects consumed a mean (±SD) of 80.5 ± 27.8 g protein/d (1.19 ± 0.44 g protein/kg body wt). Regression analysis showed a positive correlation between protein intake and qualitative ultrasound of the heel and BMD after adjustment for age, body mass index, and other nutrients. The dose-response effect was best characterized by protein consumption expressed in tertiles, such that subjects in the lowest tertile (87 g protein/d).CONCLUSION:: These data suggest that protein intakes for elderly women above current recommendations may be necessary to optimize bone mass.

AB - BACKGROUND:: The effect of protein intake on bone density is uncertain, and evidence exists for beneficial effects of both low and high protein intakes.OBJECTIVE:: The objective was to study the relation between protein consumption and bone mass in elderly women with allowance for other lifestyle factors affecting bone metabolism.DESIGN:: We conducted a cross-sectional and longitudinal study of a population-based sample of 1077 women aged 75 ± 3 y. At baseline, protein consumption was measured with a food-frequency questionnaire, and bone mass and structure were measured by using quantitative ultrasound of the heel. One year later, hip bone mineral density (BMD) was measured by using dual-energy X-ray absorptiometry.RESULTS:: Subjects consumed a mean (±SD) of 80.5 ± 27.8 g protein/d (1.19 ± 0.44 g protein/kg body wt). Regression analysis showed a positive correlation between protein intake and qualitative ultrasound of the heel and BMD after adjustment for age, body mass index, and other nutrients. The dose-response effect was best characterized by protein consumption expressed in tertiles, such that subjects in the lowest tertile (87 g protein/d).CONCLUSION:: These data suggest that protein intakes for elderly women above current recommendations may be necessary to optimize bone mass.

M3 - Article

VL - 81

SP - 1423

EP - 1428

JO - The American Journal of Clinical Nutrition

JF - The American Journal of Clinical Nutrition

SN - 0002-9165

IS - 6

ER -