Programming Effects of Excess Glucocorticoid Exposure in Late Gestation

T.J.M. Moss, Deborah Sloboda

    Research output: Chapter in Book/Conference paperChapterpeer-review

    Abstract

    Glucocorticoids are powerful hormones that play a crucial role in normal maturation of fetal organs in preparation for life outside the womb. However, exposure of the fetus to elevated levels of glucocorticoids, or exposure at inappropriate times, subtly disturbs normal fetal development. Experimental studies have demonstrated that late gestational exposure to excess glucocorticoids causes programming of a number of organ systems.
    Original languageEnglish
    Title of host publicationEarly Life Origins of Health and Disease
    EditorsMarelyn Wintour, Julie Owens
    Place of PublicationNJ, USA
    PublisherSpringer Science + Business Media
    Pages177
    ISBN (Print)0387287159
    Publication statusPublished - 2005

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