Prognostic factors in systemic lupus erythematosus

A. J G Swaak, J. C. Nossent, R. J T Smeenk

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

In the past 40 years an impressive improvement in the prognosis of SLE patients has occurred. Factors which might be responsible for this improvement are discussed. Two of the factors most frequently cited are the advances in disease recognition and treatment. However, as already noted by Albert (1979) this is questionable, as average disease duration and survival have increased in a linear fashion related to the number of publications devoted to this subject from 1950 on. Further evaluation of the literature shows that the most prominent factors which have an impact on the survival rate are specific disease manifestations (lupus nephritis) and the overall disease course (number of exacerbations). This effect of morbidity on the survival rate is greater than that of factors such as sex and race. Socio-economic factors or age at onset have no effect on the outcome.

Original languageEnglish
Pages (from-to)127-132
Number of pages6
JournalRheumatology International
Volume11
Issue number3
DOIs
Publication statusPublished - Sept 1991
Externally publishedYes
Event1ST EUROPEAN CONF ON SYSTEMIC LUPUS ERYTHEMATOSUS - AMSTERDAM, Netherlands
Duration: 15 Nov 199017 Nov 1990

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