Prognostic factors in systemic lupus erythematosus

A. J G Swaak; J. C. Nossent; R. J T Smeenk

doi:10.1007/BF00304501

Prognostic factors in systemic lupus erythematosus

A. J G Swaak, J. C. Nossent, R. J T Smeenk

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Abstract

In the past 40 years an impressive improvement in the prognosis of SLE patients has occurred. Factors which might be responsible for this improvement are discussed. Two of the factors most frequently cited are the advances in disease recognition and treatment. However, as already noted by Albert (1979) this is questionable, as average disease duration and survival have increased in a linear fashion related to the number of publications devoted to this subject from 1950 on. Further evaluation of the literature shows that the most prominent factors which have an impact on the survival rate are specific disease manifestations (lupus nephritis) and the overall disease course (number of exacerbations). This effect of morbidity on the survival rate is greater than that of factors such as sex and race. Socio-economic factors or age at onset have no effect on the outcome.

Original language	English
Pages (from-to)	127-132
Number of pages	6
Journal	Rheumatology International
Volume	11
Issue number	3
DOIs	https://doi.org/10.1007/BF00304501
Publication status	Published - Sep 1991
Externally published	Yes
Event	1ST EUROPEAN CONF ON SYSTEMIC LUPUS ERYTHEMATOSUS - AMSTERDAM, Netherlands Duration: 15 Nov 1990 → 17 Nov 1990

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10.1007/BF00304501

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title = "Prognostic factors in systemic lupus erythematosus",

abstract = "In the past 40 years an impressive improvement in the prognosis of SLE patients has occurred. Factors which might be responsible for this improvement are discussed. Two of the factors most frequently cited are the advances in disease recognition and treatment. However, as already noted by Albert (1979) this is questionable, as average disease duration and survival have increased in a linear fashion related to the number of publications devoted to this subject from 1950 on. Further evaluation of the literature shows that the most prominent factors which have an impact on the survival rate are specific disease manifestations (lupus nephritis) and the overall disease course (number of exacerbations). This effect of morbidity on the survival rate is greater than that of factors such as sex and race. Socio-economic factors or age at onset have no effect on the outcome.",

keywords = "Demographic factors, Disease recognition, Survival rate, Systemic lupus erythematosus, Treatment",

author = "Swaak, {A. J G} and Nossent, {J. C.} and Smeenk, {R. J T}",

year = "1991",

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TY - JOUR

T1 - Prognostic factors in systemic lupus erythematosus

AU - Swaak, A. J G

AU - Nossent, J. C.

AU - Smeenk, R. J T

PY - 1991/9

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N2 - In the past 40 years an impressive improvement in the prognosis of SLE patients has occurred. Factors which might be responsible for this improvement are discussed. Two of the factors most frequently cited are the advances in disease recognition and treatment. However, as already noted by Albert (1979) this is questionable, as average disease duration and survival have increased in a linear fashion related to the number of publications devoted to this subject from 1950 on. Further evaluation of the literature shows that the most prominent factors which have an impact on the survival rate are specific disease manifestations (lupus nephritis) and the overall disease course (number of exacerbations). This effect of morbidity on the survival rate is greater than that of factors such as sex and race. Socio-economic factors or age at onset have no effect on the outcome.

AB - In the past 40 years an impressive improvement in the prognosis of SLE patients has occurred. Factors which might be responsible for this improvement are discussed. Two of the factors most frequently cited are the advances in disease recognition and treatment. However, as already noted by Albert (1979) this is questionable, as average disease duration and survival have increased in a linear fashion related to the number of publications devoted to this subject from 1950 on. Further evaluation of the literature shows that the most prominent factors which have an impact on the survival rate are specific disease manifestations (lupus nephritis) and the overall disease course (number of exacerbations). This effect of morbidity on the survival rate is greater than that of factors such as sex and race. Socio-economic factors or age at onset have no effect on the outcome.

KW - Demographic factors

KW - Disease recognition

KW - Survival rate

KW - Systemic lupus erythematosus

KW - Treatment

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DO - 10.1007/BF00304501

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JO - Rheumatology International

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T2 - 1ST EUROPEAN CONF ON SYSTEMIC LUPUS ERYTHEMATOSUS

Y2 - 15 November 1990 through 17 November 1990

ER -

Prognostic factors in systemic lupus erythematosus

Abstract

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