Production of 75Se for nuclear medicine purposes using 75As(p,n)75Se nuclear reaction

M.T. Bahreyni, H. Afarideh, Pejman Rowshan Farzad

Research output: Contribution to journalArticlepeer-review

Abstract

This research has been carried out to produce selenium -75 as a result of 75As (p,n) 75Sereaction, Since 75Se-labelled radiopharmaceuticals have a wide range of applications in nuclear medicine. For this purpose, it was necessary to design a special type of backing to enable proper maintenance of the targets. In this design, compressed disks of arsenic-trioxide powder (target material) could be placed inside the backing drawer. This assembly was located in the sided grooves of the backing. After the proton bombarment of the target, selenium was separated by solvent extraction method. The results of gamma- spectrometry and paper chromatography for the determination of chemical impurities showed a high purity degree for the extracted selenium (about 0.04 ppm impurity). The optimum proton current, production yield and chemical extraction yield are suggested to be µA, 35 µCi/ µ Ah and 88% respectively.
Original languageEnglish
Pages (from-to)188-193
Number of pages5
JournalIranian Journal of Basic Medical Sciences
Volume5
Issue number3
Publication statusPublished - 2002

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