Abstract
Optimal treatment of chronic wounds requires first identifying the molecular and cellular abnormalities that prevent a chronic wound from healing and then correcting them. The principles of wound bed preparation (WBP) embodied in TIME (tissue, infection, moisture and edge), provide a systemic approach to remove molecular and cellular barriers that prevent wounds from healing. This article is a concise overview of the molecular and cellular regulation of normal wound healing and practical applications of methods of WBP to promote healing.
| Original language | English |
|---|---|
| Pages (from-to) | 171-182 |
| Journal | Primary Intention |
| Volume | 11 |
| Issue number | 4 |
| Publication status | Published - 2003 |