Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study

Gursharan Dogra; H. Herson; B. Hutchison; A.B. Irish; Christopher Heath; C. Golledge; G. Luxton; H. Moody

doi:10.1097/01.ASN.0000022890.29656.22

Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study

Gursharan Dogra, H. Herson, B. Hutchison, A.B. Irish, Christopher Heath, C. Golledge, G. Luxton, H. Moody

Research output: Contribution to journal › Article › peer-review

244 Citations (Scopus)

Abstract

Tunneled catheters are widely used for the provision of hemodialysis. Long-term catheter survival is limited by tunneled catheter-related infections (CRI). This study assesses the efficacy of catheter-restricted filling with gentamicin and citrate in preventing CRI in hemodialysis patients. A double-blind randomized study was conducted to compare heparin (5000 U/ml) with gentamicin/citrate (40 mg/ml and 3.13% citrate; ratio 2:1) as catheter-lock solutions. A total of 112 tunneled catheters in 83 patients were enrolled at the time of catheter insertion for commencement or maintenance of hemodialysis. The primary end point was CRI. Catheter malfunction, defined as blood flow rate of

Original language	English
Pages (from-to)	2133-2139
Journal	Journal of the American Society of Nephrology
Volume	13
DOIs	https://doi.org/10.1097/01.ASN.0000022890.29656.22
Publication status	Published - 2002

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Dogra, G., Herson, H., Hutchison, B., Irish, A. B., Heath, C., Golledge, C., Luxton, G., & Moody, H. (2002). Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study. Journal of the American Society of Nephrology, 13, 2133-2139. https://doi.org/10.1097/01.ASN.0000022890.29656.22

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title = "Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study",

abstract = "Tunneled catheters are widely used for the provision of hemodialysis. Long-term catheter survival is limited by tunneled catheter-related infections (CRI). This study assesses the efficacy of catheter-restricted filling with gentamicin and citrate in preventing CRI in hemodialysis patients. A double-blind randomized study was conducted to compare heparin (5000 U/ml) with gentamicin/citrate (40 mg/ml and 3.13% citrate; ratio 2:1) as catheter-lock solutions. A total of 112 tunneled catheters in 83 patients were enrolled at the time of catheter insertion for commencement or maintenance of hemodialysis. The primary end point was CRI. Catheter malfunction, defined as blood flow rate of",

author = "Gursharan Dogra and H. Herson and B. Hutchison and A.B. Irish and Christopher Heath and C. Golledge and G. Luxton and H. Moody",

year = "2002",

doi = "10.1097/01.ASN.0000022890.29656.22",

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journal = "Journal of the American Society of Nephrology",

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Dogra, G, Herson, H, Hutchison, B, Irish, AB, Heath, C, Golledge, C, Luxton, G & Moody, H 2002, 'Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study', Journal of the American Society of Nephrology, vol. 13, pp. 2133-2139. https://doi.org/10.1097/01.ASN.0000022890.29656.22

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T1 - Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study

AU - Dogra, Gursharan

AU - Herson, H.

AU - Hutchison, B.

AU - Irish, A.B.

AU - Heath, Christopher

AU - Golledge, C.

AU - Luxton, G.

AU - Moody, H.

PY - 2002

Y1 - 2002

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AB - Tunneled catheters are widely used for the provision of hemodialysis. Long-term catheter survival is limited by tunneled catheter-related infections (CRI). This study assesses the efficacy of catheter-restricted filling with gentamicin and citrate in preventing CRI in hemodialysis patients. A double-blind randomized study was conducted to compare heparin (5000 U/ml) with gentamicin/citrate (40 mg/ml and 3.13% citrate; ratio 2:1) as catheter-lock solutions. A total of 112 tunneled catheters in 83 patients were enrolled at the time of catheter insertion for commencement or maintenance of hemodialysis. The primary end point was CRI. Catheter malfunction, defined as blood flow rate of

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DO - 10.1097/01.ASN.0000022890.29656.22

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EP - 2139

JO - Journal of the American Society of Nephrology

JF - Journal of the American Society of Nephrology

ER -

Prevention of Tunneled Hemodialysis Catheter-Related Infections Using Catheter-Restricted Filling with Gentamicin and Citrate: A Randomized Controlled Study

Abstract

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