Prevalence of restless legs syndrome in a tertiary cohort of ambulant patients with chronic liver disease

Michael X. Ma, Yi Huang, Leon A. Adams, Robert Gilpin, George Garas, Gerry MacQuillan, Gary P. Jeffrey, Ross Mac Nicholas

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A cross-sectional survey of 188 ambulant patients with chronic liver disease was performed to determine the prevalence of restless legs syndrome (RLS) using a validated patient completed questionnaire. Patient responses were verified by standardised telephone interview. RLS was identified in 64 (34%) patients. Significantly, more patients with cirrhosis had RLS than patients without RLS (43.9 vs 23.3%, P = 0.003, respectively). Cirrhotic patients with a history of hepatic encephalopathy were also more likely to have RLS than patients without hepatic encephalopathy (odds ratio = 4.33, 95% confidence interval = 1.40–13.37, P = 0.011). Patients with chronic liver disease may be at risk for RLS; early detection and treatment may improve patient outcomes.

Original languageEnglish
Pages (from-to)347-350
Number of pages4
JournalInternal Medicine Journal
Volume48
Issue number3
DOIs
Publication statusPublished - 1 Mar 2018

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