TY - JOUR
T1 - Prevalence of metabolic syndrome among Australians with severe mental illness
AU - John, Alexander P.
AU - Koloth, Radhakrishnan
AU - Dragovic, Milan
AU - Lim, Stephen C.B.
PY - 2009
Y1 - 2009
N2 - Objective: To assess the prevalence of metabolic syndrome and its association with sociodemographic, clinical and lifestyle variables among Australian patients with a variety of psychiatric disorders.Design and setting: Cross-sectional study of patients attending a public mental health service in Western Australia between July 2005 and September 2006.Participants: Patients who were aged 18–65 years; diagnosed with schizophrenia, schizoaffective disorder, bipolar disorder, major depressive disorder with psychotic symptoms, drug-induced psychosis or borderline personality disorder; and currently taking at least one antipsychotic drug for a minimum of 2 weeks.Main outcome measures: Prevalence of metabolic syndrome diagnosed with International Diabetes Federation criteria; fasting blood glucose and lipid levels; sociodemographic and lifestyle characteristics.Results: Of 219 patients invited to participate, 203 agreed and had complete data. Prevalence of metabolic syndrome was 54% overall, and highest among patients with bipolar disorder or schizoaffective disorder (both 67%), followed by schizophrenia (51%). Sociodemographic variables, including age and ethnic background, were not significantly associated with metabolic syndrome, but a strong association was seen with mean body mass index. Other cardiovascular risk factors, such as smoking and substance misuse, were common among participants.Conclusions: Prevalence of metabolic syndrome in this population was almost double that in the general Australian population, and patients with schizophrenia had a prevalence among the highest in the developed world. Prevalence was also high in patients with a variety of other psychiatric disorders.
AB - Objective: To assess the prevalence of metabolic syndrome and its association with sociodemographic, clinical and lifestyle variables among Australian patients with a variety of psychiatric disorders.Design and setting: Cross-sectional study of patients attending a public mental health service in Western Australia between July 2005 and September 2006.Participants: Patients who were aged 18–65 years; diagnosed with schizophrenia, schizoaffective disorder, bipolar disorder, major depressive disorder with psychotic symptoms, drug-induced psychosis or borderline personality disorder; and currently taking at least one antipsychotic drug for a minimum of 2 weeks.Main outcome measures: Prevalence of metabolic syndrome diagnosed with International Diabetes Federation criteria; fasting blood glucose and lipid levels; sociodemographic and lifestyle characteristics.Results: Of 219 patients invited to participate, 203 agreed and had complete data. Prevalence of metabolic syndrome was 54% overall, and highest among patients with bipolar disorder or schizoaffective disorder (both 67%), followed by schizophrenia (51%). Sociodemographic variables, including age and ethnic background, were not significantly associated with metabolic syndrome, but a strong association was seen with mean body mass index. Other cardiovascular risk factors, such as smoking and substance misuse, were common among participants.Conclusions: Prevalence of metabolic syndrome in this population was almost double that in the general Australian population, and patients with schizophrenia had a prevalence among the highest in the developed world. Prevalence was also high in patients with a variety of other psychiatric disorders.
KW - Adolescent
KW - Adult
KW - Aged
KW - Body Weight
KW - Cross-Sectional Studies
KW - Female
KW - Humans
KW - Life Style
KW - Male
KW - Mental Disorders/complications
KW - Mental Health Services/statistics & numerical data
KW - Metabolic Syndrome/complications
KW - Middle Aged
KW - Prevalence
KW - Psychometrics
KW - Risk Factors
KW - Schizophrenia/complications
KW - Severity of Illness Index
KW - Socioeconomic Factors
KW - Surveys and Questionnaires
KW - Waist Circumference
KW - Western Australia/epidemiology
KW - Young Adult
UR - http://www.scopus.com/inward/record.url?scp=61849124608&partnerID=8YFLogxK
U2 - 10.5694/j.1326-5377.2009.tb02342.x
DO - 10.5694/j.1326-5377.2009.tb02342.x
M3 - Article
C2 - 19220180
SN - 0025-729X
VL - 190
SP - 176
EP - 179
JO - Medical Journal of Australia
JF - Medical Journal of Australia
IS - 4
ER -