Prevalence of demodex infestation in chronic blepharitis

H Mohammad-Rabei, N Behnaz, MA Javadi, D Roshandel, S Feizi, Z Ghadyani, M Emamverdi

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Purpose: To determine the prevalence of demodex infestation in patients with chronic blepharitis versus normal subjects in Iranian population.
Methods: In this case-control study, 203 consecutive patients in Torfeh and Labbafinejad Hospitals in Tehran in 2017 were enrolled and the prevalence of demodex infestation in patients with chronic blepharitis (n=102 patients) versus normal population (n=101 subjects) was determined. Demographic data, Clinical signs and symptoms was documented for every subject. Lash sampling was performed by epilating the lashes. Every eyelash has cylindrical dandruff was chosen to epilate .totally four lashes were collected from each patient, two lashes from superior eyelid and two from inferior eyelid. Then the collected lashes were inspected for Demodex based on morphology using a light microscope at the magnification 40 and 100 .The time interval between sampling and observation was less than 12 h in all cases. The main outcome measure was the prevalence of demodex infestation in each study group.
Results: The prevalence of Demodex in total study group is 26.1% and the prevalence in blepharitis group is 26.5% and in control group is 25.7% without statistically significant difference (P > 0.05). Demodex presence was related to older age, cylindrical, and some clinical symptoms such as ocular burning, and itching (P>0.05).
Conclusion: Totally, according to the obtained results it may be concluded that demodex infestation may not related to chronic blepharitis significantly. Prevalence of demodex infestation was increased by aging and it has negative association with oily scales.
Original languageEnglish
Pages (from-to)3-8
Number of pages6
JournalBina Journal of Ophthalmology
Issue number1
Publication statusPublished - 2018
Externally publishedYes


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