TY - JOUR
T1 - Preterm human milk composition: A systematic literature review
AU - Boyce, Catherine
AU - Watson, Mistral
AU - Lazidis, Grace
AU - Reeve, Sarah
AU - Dods, K.
AU - Simmer, Karen
AU - McLeod, G.
PY - 2016/9/28
Y1 - 2016/9/28
N2 - © The Authors 2016.There are wide variations in the macronutrient values adopted by neonatal intensive care units and industry to fortify milk in efforts to achieve recommended intakes for preterm infants. Contributing to this is the variation in macronutrient composition of preterm milk between and within mothers and the variable quality of milk analyses used to determine the macronutrient content of milk. We conducted a systematic review of the literature using articles published in English between 1959 and 2013 that reported the concentrations of one or more macronutrients or energy content in human preterm milk, sampled over a representative 24-h period. Searched medical databases included Ovid Medline, Scopus, CINAHL and the Cochrane Library. Results are presented as mean values and ranges for each macronutrient during weeks 1-8 of lactation, and preferred mean values (g/100 ml) for colostrum (week 1) and mature milk (weeks 2-8; protein: 1·27, fat: 3·46, lactose: 6·15 and carbohydrate: 7·34), using data from studies employing the highest-quality analyses. Industry-directed fortification practices using these mean values fail to meet protein targets for infants weighing
AB - © The Authors 2016.There are wide variations in the macronutrient values adopted by neonatal intensive care units and industry to fortify milk in efforts to achieve recommended intakes for preterm infants. Contributing to this is the variation in macronutrient composition of preterm milk between and within mothers and the variable quality of milk analyses used to determine the macronutrient content of milk. We conducted a systematic review of the literature using articles published in English between 1959 and 2013 that reported the concentrations of one or more macronutrients or energy content in human preterm milk, sampled over a representative 24-h period. Searched medical databases included Ovid Medline, Scopus, CINAHL and the Cochrane Library. Results are presented as mean values and ranges for each macronutrient during weeks 1-8 of lactation, and preferred mean values (g/100 ml) for colostrum (week 1) and mature milk (weeks 2-8; protein: 1·27, fat: 3·46, lactose: 6·15 and carbohydrate: 7·34), using data from studies employing the highest-quality analyses. Industry-directed fortification practices using these mean values fail to meet protein targets for infants weighing
UR - http://www.scopus.com/inward/record.url?scp=84982105673&partnerID=8YFLogxK
U2 - 10.1017/S0007114516003007
DO - 10.1017/S0007114516003007
M3 - Review article
C2 - 27522863
SN - 0007-1145
VL - 116
SP - 1033
EP - 1045
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 6
ER -