Pregnancy after breast cancer: Are young patients willing to participate in clinical studies?

O. Pagani; M. Ruggeri; S. Manunta; Christobel Saunders; F. Peccatori; F. Cardoso; B. Kaufman; S. Paluch-Shimon; H. Gewefel; E. Gallerani; O. Abulkhair; B. Pistilli; E. Warner; E. Saloustros; L. Perey; K. Zaman; M. Rabaglio; S. Gelber; R.D. Gelber; A. Goldhirsch; L. Korde; H.A. Azim; A.H. Partridge

doi:10.1016/j.breast.2015.01.005

Pregnancy after breast cancer: Are young patients willing to participate in clinical studies?

O. Pagani, M. Ruggeri, S. Manunta, Christobel Saunders, F. Peccatori, F. Cardoso, B. Kaufman, S. Paluch-Shimon, H. Gewefel, E. Gallerani, O. Abulkhair, B. Pistilli, E. Warner, E. Saloustros, L. Perey, K. Zaman, M. Rabaglio, S. Gelber, R.D. Gelber, A. GoldhirschL. Korde, H.A. Azim, A.H. Partridge

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Abstract

© 2015 Elsevier Ltd. Young patients with breast cancer (BC) are often concerned about treatment-induced infertility and express maternity desire. Conception after BC does not seem to affect outcome, but information in estrogen-receptor positive (ER+) disease is not definitive. From September 2012-March 2013, 212 evaluable patients with ER+ early BC, 30 months was higher (83%) than in older women (14%), interest was independent of age in patients treated for ≤30 months. A prospective study in this patient population seems relevant and feasible. The International-Breast-Cancer-Study-Group (IBCSG), within the Breast-International-Group (BIG) - North-American-Breast-Cancer-Groups (NABCG) collaboration, is launching a study (POSITIVE) addressing ET interruption to allow pregnancy.

Original language	English
Pages (from-to)	201-207
Journal	BREAST
Volume	24
Issue number	3
DOIs	https://doi.org/10.1016/j.breast.2015.01.005
Publication status	Published - 2015

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Cite this

Pagani, O., Ruggeri, M., Manunta, S., Saunders, C., Peccatori, F., Cardoso, F., Kaufman, B., Paluch-Shimon, S., Gewefel, H., Gallerani, E., Abulkhair, O., Pistilli, B., Warner, E., Saloustros, E., Perey, L., Zaman, K., Rabaglio, M., Gelber, S., Gelber, R. D., ... Partridge, A. H. (2015). Pregnancy after breast cancer: Are young patients willing to participate in clinical studies? BREAST, 24(3), 201-207. https://doi.org/10.1016/j.breast.2015.01.005

@article{63388cd808d744ae915506ca8d561f6b,

title = "Pregnancy after breast cancer: Are young patients willing to participate in clinical studies?",

abstract = "{\textcopyright} 2015 Elsevier Ltd. Young patients with breast cancer (BC) are often concerned about treatment-induced infertility and express maternity desire. Conception after BC does not seem to affect outcome, but information in estrogen-receptor positive (ER+) disease is not definitive. From September 2012-March 2013, 212 evaluable patients with ER+ early BC, 30 months was higher (83%) than in older women (14%), interest was independent of age in patients treated for ≤30 months. A prospective study in this patient population seems relevant and feasible. The International-Breast-Cancer-Study-Group (IBCSG), within the Breast-International-Group (BIG) - North-American-Breast-Cancer-Groups (NABCG) collaboration, is launching a study (POSITIVE) addressing ET interruption to allow pregnancy.",

author = "O. Pagani and M. Ruggeri and S. Manunta and Christobel Saunders and F. Peccatori and F. Cardoso and B. Kaufman and S. Paluch-Shimon and H. Gewefel and E. Gallerani and O. Abulkhair and B. Pistilli and E. Warner and E. Saloustros and L. Perey and K. Zaman and M. Rabaglio and S. Gelber and R.D. Gelber and A. Goldhirsch and L. Korde and H.A. Azim and A.H. Partridge",

year = "2015",

doi = "10.1016/j.breast.2015.01.005",

language = "English",

volume = "24",

pages = "201--207",

journal = "BREAST",

issn = "0960-9776",

publisher = "Churchill Livingstone",