Postmitotic Cone Migration Mechanisms in the Mammalian Retina

Livia S. Carvalho, Carla B. Mellough

Research output: Chapter in Book/Conference paperConference paperpeer-review

1 Citation (Scopus)

Abstract

High visual acuity and the ability to identify colours is solely dependent upon healthy cone photoreceptors in the retina. Little is known about cone migration mechanisms during postmitotic retinal maturation which, if it occurs erroneously, can result in non-functional cells and altered vision. This review provides an overview of neuronal and cone somal migration mechanisms and the potential molecular partners and nuclear structures driving this process. Furthermore, it will also review foveal formation and how that differs from peripheral cone migration in the human retina.

Original languageEnglish
Title of host publicationRetinal Degenerative Diseases
Subtitle of host publicationMechanisms and Experimental Therapy
EditorsCatherine Bowes Rickman, Christian Grimm, Robert E. Anderson, John D. Ash, Matthew M. LaVail
Place of PublicationAustria
PublisherSpringer
Chapter80
Pages489-493
Number of pages5
ISBN (Electronic)9783030273781
ISBN (Print)9783030273774
DOIs
Publication statusPublished - 1 Jan 2019
EventXVIII International Symposium on Retinal Degeneration 2018 - Killarney, Ireland
Duration: 3 Sept 20188 Sept 2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1185
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Conference

ConferenceXVIII International Symposium on Retinal Degeneration 2018
Abbreviated titleRD 2018
Country/TerritoryIreland
CityKillarney
Period3/09/188/09/18

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