TY - JOUR
T1 - POST-OPERATIVE SPORT PARTICIPATION AND SATISFACTION WITH RETURN TO ACTIVITY AFTER MATRIX-INDUCED AUTOLOGOUS CHONDROCYTE IMPLANTATION IN THE KNEE
AU - Ebert, Jay R.
AU - Janes, Gregory C.
AU - Wood, David J.
PY - 2020/2
Y1 - 2020/2
N2 - Background: Returning to a satisfactory activity level is expected by patients after cartilage repair, and may define overall surgical success.Purpose: To investigate: 1) the level and improvement in activity in patients at two years after matrix-induced autologous chondrocyte implantation (MACI), 2) what factors are associated with post-operative (and improvement in) activity level, and 3) whether patients are satisfied with their ability to participate in recreational and/or sporting activities.Study Design: Prospective cohort.Methods: One hundred and fifty patients that underwent MACI were included in this analysis (83 tibiofemoral and 67 patellofemoral). All patients completed the Tegner Activity Scale (TAS) and the Knee Injury and Osteoarthritis Outcome Score (KOOS) presurgery and at two years (range: 24-26 months) post-surgery, as well as a questionnaire evaluating satisfaction with their ability to return to recreational and sporting activities.Results: The TAS significantly improved (p= 1 point on the TAS, while 121 patients (81%) improved >= 10 points on the KOOS Sport, previously reported as the minimal detectable change for each. Patient age, duration of symptoms (DOS) and gender were associated with post-operative activity level, though body mass index (BMI), defect size and concomitant procedures were not. Overall, 128 patients (85%) were satisfied with their ability to return to recreational activities, with 99 (66%) satisfied with sport participation. The two-year TAS, and TAS improvement, were significantly associated with satisfaction in performing recreational activities (two-year TAS, rho=-0.42, pConclusions: The TAS and KOOS Sport significantly improved after MACI, though only 59% of patients improved >= 1 point on the TAS. Despite this, 85% and 66% of patients were satisfied with their ability to return to recreational activities and participate in sport, respectively. Age, DOS and gender were associated with activity, and overall these findings can be used to provide realistic activity expectations to patients undergoing MACI.
AB - Background: Returning to a satisfactory activity level is expected by patients after cartilage repair, and may define overall surgical success.Purpose: To investigate: 1) the level and improvement in activity in patients at two years after matrix-induced autologous chondrocyte implantation (MACI), 2) what factors are associated with post-operative (and improvement in) activity level, and 3) whether patients are satisfied with their ability to participate in recreational and/or sporting activities.Study Design: Prospective cohort.Methods: One hundred and fifty patients that underwent MACI were included in this analysis (83 tibiofemoral and 67 patellofemoral). All patients completed the Tegner Activity Scale (TAS) and the Knee Injury and Osteoarthritis Outcome Score (KOOS) presurgery and at two years (range: 24-26 months) post-surgery, as well as a questionnaire evaluating satisfaction with their ability to return to recreational and sporting activities.Results: The TAS significantly improved (p= 1 point on the TAS, while 121 patients (81%) improved >= 10 points on the KOOS Sport, previously reported as the minimal detectable change for each. Patient age, duration of symptoms (DOS) and gender were associated with post-operative activity level, though body mass index (BMI), defect size and concomitant procedures were not. Overall, 128 patients (85%) were satisfied with their ability to return to recreational activities, with 99 (66%) satisfied with sport participation. The two-year TAS, and TAS improvement, were significantly associated with satisfaction in performing recreational activities (two-year TAS, rho=-0.42, pConclusions: The TAS and KOOS Sport significantly improved after MACI, though only 59% of patients improved >= 1 point on the TAS. Despite this, 85% and 66% of patients were satisfied with their ability to return to recreational activities and participate in sport, respectively. Age, DOS and gender were associated with activity, and overall these findings can be used to provide realistic activity expectations to patients undergoing MACI.
KW - Chondral defect
KW - clinical outcomes
KW - matrix-induced autologous chondrocyte implantation
KW - movement system
KW - patient satisfaction
KW - return to sport
KW - ARTICULAR-CARTILAGE REPAIR
KW - TEGNER ACTIVITY SCALE
KW - OUTCOMES
KW - SCORE
KW - TRANSPLANTATION
KW - RESPONSIVENESS
KW - RELIABILITY
KW - VALIDITY
KW - DEFECTS
KW - INJURY
U2 - 10.26603/ijspt20200001
DO - 10.26603/ijspt20200001
M3 - Article
VL - 15
SP - 1
EP - 11
JO - The International Journal of Sports Physical Therapy
JF - The International Journal of Sports Physical Therapy
SN - 2159-2896
IS - 1
ER -