Plant mitochondrial protein import: The ins and outs

Abi S. Ghifari, Mabel Gill-Hille, Monika W. Murcha

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The majority of the mitochondrial proteome, required to fulfil its diverse range of functions, is cytosolically synthesised and translocated via specialised machinery. The dedicated translocases, receptors, and associated proteins have been characterised in great detail in yeast over the last several decades, yet many of the mechanisms that regulate these processes in higher eukaryotes are still unknown. In this review, we highlight the current knowledge of mitochondrial protein import in plants. Despite the fact that the mechanisms of mitochondrial protein import have remained conserved across species, many unique features have arisen in plants to encompass the developmental, tissue-specific, and stress-responsive regulation in planta. An understanding of unique features and mechanisms in plants provides us with a unique insight into the regulation of mitochondrial biogenesis in higher eukaryotes.

Original languageEnglish
Pages (from-to)2191-2208
Number of pages18
JournalBiochemical Journal
Volume475
Issue number13
DOIs
Publication statusPublished - 16 Jul 2018

Fingerprint

Plant Proteins
Mitochondrial Proteins
Eukaryota
Proteome
Yeast
Machinery
Organelle Biogenesis
Tissue
Yeasts
Proteins

Cite this

@article{e30ebcaf67b64c97a5985fb6a5274ecb,
title = "Plant mitochondrial protein import: The ins and outs",
abstract = "The majority of the mitochondrial proteome, required to fulfil its diverse range of functions, is cytosolically synthesised and translocated via specialised machinery. The dedicated translocases, receptors, and associated proteins have been characterised in great detail in yeast over the last several decades, yet many of the mechanisms that regulate these processes in higher eukaryotes are still unknown. In this review, we highlight the current knowledge of mitochondrial protein import in plants. Despite the fact that the mechanisms of mitochondrial protein import have remained conserved across species, many unique features have arisen in plants to encompass the developmental, tissue-specific, and stress-responsive regulation in planta. An understanding of unique features and mechanisms in plants provides us with a unique insight into the regulation of mitochondrial biogenesis in higher eukaryotes.",
author = "Ghifari, {Abi S.} and Mabel Gill-Hille and Murcha, {Monika W.}",
year = "2018",
month = "7",
day = "16",
doi = "10.1042/BCJ20170521",
language = "English",
volume = "475",
pages = "2191--2208",
journal = "The Biochemical journal",
issn = "0264-6021",
publisher = "Portland Press Ltd.",
number = "13",

}

Plant mitochondrial protein import : The ins and outs. / Ghifari, Abi S.; Gill-Hille, Mabel; Murcha, Monika W.

In: Biochemical Journal, Vol. 475, No. 13, 16.07.2018, p. 2191-2208.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Plant mitochondrial protein import

T2 - The ins and outs

AU - Ghifari, Abi S.

AU - Gill-Hille, Mabel

AU - Murcha, Monika W.

PY - 2018/7/16

Y1 - 2018/7/16

N2 - The majority of the mitochondrial proteome, required to fulfil its diverse range of functions, is cytosolically synthesised and translocated via specialised machinery. The dedicated translocases, receptors, and associated proteins have been characterised in great detail in yeast over the last several decades, yet many of the mechanisms that regulate these processes in higher eukaryotes are still unknown. In this review, we highlight the current knowledge of mitochondrial protein import in plants. Despite the fact that the mechanisms of mitochondrial protein import have remained conserved across species, many unique features have arisen in plants to encompass the developmental, tissue-specific, and stress-responsive regulation in planta. An understanding of unique features and mechanisms in plants provides us with a unique insight into the regulation of mitochondrial biogenesis in higher eukaryotes.

AB - The majority of the mitochondrial proteome, required to fulfil its diverse range of functions, is cytosolically synthesised and translocated via specialised machinery. The dedicated translocases, receptors, and associated proteins have been characterised in great detail in yeast over the last several decades, yet many of the mechanisms that regulate these processes in higher eukaryotes are still unknown. In this review, we highlight the current knowledge of mitochondrial protein import in plants. Despite the fact that the mechanisms of mitochondrial protein import have remained conserved across species, many unique features have arisen in plants to encompass the developmental, tissue-specific, and stress-responsive regulation in planta. An understanding of unique features and mechanisms in plants provides us with a unique insight into the regulation of mitochondrial biogenesis in higher eukaryotes.

UR - http://www.scopus.com/inward/record.url?scp=85050362576&partnerID=8YFLogxK

U2 - 10.1042/BCJ20170521

DO - 10.1042/BCJ20170521

M3 - Review article

VL - 475

SP - 2191

EP - 2208

JO - The Biochemical journal

JF - The Biochemical journal

SN - 0264-6021

IS - 13

ER -