Physical characteristics and developmental capacity of oocytes and embryos following human in vitro maturation.

Melanie Lisa Walls

Physical characteristics and developmental capacity of oocytes and embryos following human in vitro maturation.

Melanie Lisa Walls

Research output: Thesis › Doctoral Thesis

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Abstract

The aim was to compare the performance of in-vitro maturation (IVM) with in-vitro fertilisation (IVF) for patients with polycystic ovary syndrome (PCOS). Differences between IVM and IVF were investigated with regard to oocyte and embryo development, morphometric kinetics, live-birth rates, neonatal outcomes and the effects of the use of maternal serum for IVM culture. The findings of this thesis demonstrate that although IVM treatment is still inferior to IVF in some aspects, methodological advances have improved success rates markedly, particularly for frozen embryo treatment cycles. IVM is an effective option for treating PCOS infertility.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Keelan, Jeff, Supervisor Hart, Roger, Supervisor Ryan, John, Supervisor
Award date	18 Dec 2016
Publication status	Unpublished - 2016

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THESIS - DOCTOR OF PHILOSOPHY - WALLS Melanie Lisa - 2016
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title = "Physical characteristics and developmental capacity of oocytes and embryos following human in vitro maturation.",

abstract = "The aim was to compare the performance of in-vitro maturation (IVM) with in-vitro fertilisation (IVF) for patients with polycystic ovary syndrome (PCOS). Differences between IVM and IVF were investigated with regard to oocyte and embryo development, morphometric kinetics, live-birth rates, neonatal outcomes and the effects of the use of maternal serum for IVM culture. The findings of this thesis demonstrate that although IVM treatment is still inferior to IVF in some aspects, methodological advances have improved success rates markedly, particularly for frozen embryo treatment cycles. IVM is an effective option for treating PCOS infertility. ",

keywords = "In vitro maturation, Polycystic ovary syndrome, Oocyte, Pregnancy, In vitro fertilisation, Morphokinetcs, assisted reproduction",

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TY - BOOK

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AU - Walls, Melanie Lisa

PY - 2016

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N2 - The aim was to compare the performance of in-vitro maturation (IVM) with in-vitro fertilisation (IVF) for patients with polycystic ovary syndrome (PCOS). Differences between IVM and IVF were investigated with regard to oocyte and embryo development, morphometric kinetics, live-birth rates, neonatal outcomes and the effects of the use of maternal serum for IVM culture. The findings of this thesis demonstrate that although IVM treatment is still inferior to IVF in some aspects, methodological advances have improved success rates markedly, particularly for frozen embryo treatment cycles. IVM is an effective option for treating PCOS infertility.

AB - The aim was to compare the performance of in-vitro maturation (IVM) with in-vitro fertilisation (IVF) for patients with polycystic ovary syndrome (PCOS). Differences between IVM and IVF were investigated with regard to oocyte and embryo development, morphometric kinetics, live-birth rates, neonatal outcomes and the effects of the use of maternal serum for IVM culture. The findings of this thesis demonstrate that although IVM treatment is still inferior to IVF in some aspects, methodological advances have improved success rates markedly, particularly for frozen embryo treatment cycles. IVM is an effective option for treating PCOS infertility.

KW - In vitro maturation

KW - Polycystic ovary syndrome

KW - Oocyte

KW - Pregnancy

KW - In vitro fertilisation

KW - Morphokinetcs

KW - assisted reproduction

M3 - Doctoral Thesis

ER -

Physical characteristics and developmental capacity of oocytes and embryos following human in vitro maturation.

Abstract

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