Phenolic acid metabolites as biomarkers for tea- and coffee-drived polyphenol exposure in human subjects

Jonathan Hodgson; S.Y. Chan; Ian Puddey; A. Devine; N. Wattanapenpaiboon; M.L. Wahlqvist; W. Lukito; Valerie Burke; Natalie Ward; Richard Prince; Kevin Croft

doi:10.1079/BJN20031046

Phenolic acid metabolites as biomarkers for tea- and coffee-drived polyphenol exposure in human subjects

Jonathan Hodgson, S.Y. Chan, Ian Puddey, A. Devine, N. Wattanapenpaiboon, M.L. Wahlqvist, W. Lukito, Valerie Burke, Natalie Ward, Richard Prince, Kevin Croft

Research output: Contribution to journal › Article › peer-review

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Abstract

Tea and coffee are rich in polyphenols with a variety of biological activities. Many of the demonstrated activities are consistent with favourable effects on the risk of chronic diseases. 4-O-methylgallic acid (4OMGA) and isoferulic acid are potential biomarkers of exposure to polyphenols derived from tea and coffee respectively. 4OMGA is derived from gallic acid in tea, and isoferulic acid is derived from chlorogenic acid in coffee. Our major objective was to explore the relationships of tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid in human subjects. The relationships of long-term usual (111 participants) and contemporaneously recorded current (344 participants) tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid were assessed in two populations. 4OMGA was related to usual (r 0·50, P

Original language	English
Pages (from-to)	301-305
Journal	British Journal of Nutrition
Volume	91
Issue number	2
DOIs	https://doi.org/10.1079/BJN20031046
Publication status	Published - 2004

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10.1079/BJN20031046

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title = "Phenolic acid metabolites as biomarkers for tea- and coffee-drived polyphenol exposure in human subjects",

abstract = "Tea and coffee are rich in polyphenols with a variety of biological activities. Many of the demonstrated activities are consistent with favourable effects on the risk of chronic diseases. 4-O-methylgallic acid (4OMGA) and isoferulic acid are potential biomarkers of exposure to polyphenols derived from tea and coffee respectively. 4OMGA is derived from gallic acid in tea, and isoferulic acid is derived from chlorogenic acid in coffee. Our major objective was to explore the relationships of tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid in human subjects. The relationships of long-term usual (111 participants) and contemporaneously recorded current (344 participants) tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid were assessed in two populations. 4OMGA was related to usual (r 0·50, P",

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doi = "10.1079/BJN20031046",

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T1 - Phenolic acid metabolites as biomarkers for tea- and coffee-drived polyphenol exposure in human subjects

AU - Hodgson, Jonathan

AU - Chan, S.Y.

AU - Puddey, Ian

AU - Devine, A.

AU - Wattanapenpaiboon, N.

AU - Wahlqvist, M.L.

AU - Lukito, W.

AU - Burke, Valerie

AU - Ward, Natalie

AU - Prince, Richard

AU - Croft, Kevin

PY - 2004

Y1 - 2004

N2 - Tea and coffee are rich in polyphenols with a variety of biological activities. Many of the demonstrated activities are consistent with favourable effects on the risk of chronic diseases. 4-O-methylgallic acid (4OMGA) and isoferulic acid are potential biomarkers of exposure to polyphenols derived from tea and coffee respectively. 4OMGA is derived from gallic acid in tea, and isoferulic acid is derived from chlorogenic acid in coffee. Our major objective was to explore the relationships of tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid in human subjects. The relationships of long-term usual (111 participants) and contemporaneously recorded current (344 participants) tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid were assessed in two populations. 4OMGA was related to usual (r 0·50, P

AB - Tea and coffee are rich in polyphenols with a variety of biological activities. Many of the demonstrated activities are consistent with favourable effects on the risk of chronic diseases. 4-O-methylgallic acid (4OMGA) and isoferulic acid are potential biomarkers of exposure to polyphenols derived from tea and coffee respectively. 4OMGA is derived from gallic acid in tea, and isoferulic acid is derived from chlorogenic acid in coffee. Our major objective was to explore the relationships of tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid in human subjects. The relationships of long-term usual (111 participants) and contemporaneously recorded current (344 participants) tea and coffee intake with 24 h urinary excretion of 4OMGA and isoferulic acid were assessed in two populations. 4OMGA was related to usual (r 0·50, P

U2 - 10.1079/BJN20031046

DO - 10.1079/BJN20031046

M3 - Article

SN - 0007-1145

VL - 91

SP - 301

EP - 305

JO - British Journal of Nutrition

JF - British Journal of Nutrition

IS - 2

ER -

Phenolic acid metabolites as biomarkers for tea- and coffee-drived polyphenol exposure in human subjects

Abstract

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