Pharmacists' response to anaphylaxis in the community (PRAC): A randomised, simulated patient study of pharmacist practice

Sandra Salter, B. Delfante, Sarah De Klerk, Frank Sanfilippo, Rhonda Clifford

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Objective: To evaluate how community pharmacists manage patients with anaphylaxis. Design: A randomised, cross-sectional, simulated patient study of community pharmacist practice. Setting: 300 metropolitan pharmacies located in Perth Australia, randomised to three groups of 100 pharmacies. Each group corresponded to a different epinephrine autoinjector: original EpiPen, new-look EpiPen or Anapen. Participants: 300 pharmacies were visited with 271 simulated patient visits included in the final analysis (88=original EpiPen, 92=new-look EpiPen, 91=Anapen). Outcome measures: Primary anaphylaxis preparedness (readiness to treat acute anaphylaxis). Secondary anaphylaxis engagement (willingness to engage the patient in a discussion about their anaphylaxis). Methods: Simulated patients approached pharmacists, using a standardised scenario, for assistance with epinephrine autoinjector use and advice about the use of antihistamines in anaphylaxis. Scores for each outcome were obtained based on the number of predefined statements addressed by the pharmacist during the consultation (maximum score=5 for preparedness and 8 for engagement). Results: The mean anaphylaxis preparedness score was 2.39 points (SD 1.17). Scores for new-look EpiPen were significantly higher than for original EpiPen and Anapen (2.75 vs 2.38 points, p=0.027; 2.75 vs 2.03 points, p
Original languageEnglish
Pages (from-to)10pp
JournalBMJ Open
Issue number7
Publication statusPublished - 2014


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