Perspectives on hand function in girls and women with Rett syndrome

Jennepher Downs, S Parkinson, S Ranelli, Helen Leonard, P Diener, M Lotan

Research output: Contribution to journalLiterature review

7 Citations (Scopus)
405 Downloads (Pure)

Abstract

Objective: Rett syndrome is a rare neurodevelopmental disorder that is usually associated with a mutation on the X-linked MECP2 gene. Hand function is particularly affected and we discuss theoretical and practical perspectives for optimising hand function in Rett syndrome.

Methods: We reviewed the literature pertaining to hand function and stereotypies in Rett syndrome and developed a toolkit for their assessment and treatment.

Results: There is little published information on management of hand function in Rett syndrome. We suggest assessment and treatment strategies based on available literature, clinical experience and grounded in theories of motor control and motor learning.

Conclusion: Additional studies are needed to determine the best treatments for hand function in Rett syndrome. Meanwhile, clinical needs can be addressed by supplementing the evidence base with an understanding of the complexities of Rett syndrome, clinical experience, environmental enrichment animal studies and theories of motor control and motor learning.


Original languageEnglish
Pages (from-to)210-217
JournalDevelopmental Neurorehabilitation
Volume17
Issue number3
DOIs
Publication statusPublished - Jun 2014

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Rett Syndrome
Hand
Learning
X-Linked Genes
Information Management
Therapeutics
Mutation

Cite this

Downs, Jennepher ; Parkinson, S ; Ranelli, S ; Leonard, Helen ; Diener, P ; Lotan, M. / Perspectives on hand function in girls and women with Rett syndrome. In: Developmental Neurorehabilitation. 2014 ; Vol. 17, No. 3. pp. 210-217.
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Perspectives on hand function in girls and women with Rett syndrome. / Downs, Jennepher; Parkinson, S; Ranelli, S; Leonard, Helen; Diener, P; Lotan, M.

In: Developmental Neurorehabilitation, Vol. 17, No. 3, 06.2014, p. 210-217.

Research output: Contribution to journalLiterature review

TY - JOUR

T1 - Perspectives on hand function in girls and women with Rett syndrome

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AU - Parkinson, S

AU - Ranelli, S

AU - Leonard, Helen

AU - Diener, P

AU - Lotan, M

PY - 2014/6

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N2 - Objective: Rett syndrome is a rare neurodevelopmental disorder that is usually associated with a mutation on the X-linked MECP2 gene. Hand function is particularly affected and we discuss theoretical and practical perspectives for optimising hand function in Rett syndrome. Methods: We reviewed the literature pertaining to hand function and stereotypies in Rett syndrome and developed a toolkit for their assessment and treatment. Results: There is little published information on management of hand function in Rett syndrome. We suggest assessment and treatment strategies based on available literature, clinical experience and grounded in theories of motor control and motor learning. Conclusion: Additional studies are needed to determine the best treatments for hand function in Rett syndrome. Meanwhile, clinical needs can be addressed by supplementing the evidence base with an understanding of the complexities of Rett syndrome, clinical experience, environmental enrichment animal studies and theories of motor control and motor learning.

AB - Objective: Rett syndrome is a rare neurodevelopmental disorder that is usually associated with a mutation on the X-linked MECP2 gene. Hand function is particularly affected and we discuss theoretical and practical perspectives for optimising hand function in Rett syndrome. Methods: We reviewed the literature pertaining to hand function and stereotypies in Rett syndrome and developed a toolkit for their assessment and treatment. Results: There is little published information on management of hand function in Rett syndrome. We suggest assessment and treatment strategies based on available literature, clinical experience and grounded in theories of motor control and motor learning. Conclusion: Additional studies are needed to determine the best treatments for hand function in Rett syndrome. Meanwhile, clinical needs can be addressed by supplementing the evidence base with an understanding of the complexities of Rett syndrome, clinical experience, environmental enrichment animal studies and theories of motor control and motor learning.

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